Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912680003> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2912680003 endingPage "255" @default.
- W2912680003 startingPage "239" @default.
- W2912680003 abstract "Molecular pharmacoepidemiology is the study of the manner in which molecular biomarkers alter the clinical effects of medications in populations. This chapter discusses the features of molecular pharmacoepidemiology that are unique to the field. Molecular pharmacoepidemiology focuses on the effects of genetics on clinical outcomes and uses larger observational and experimental methods to evaluate the effectiveness and safety of drug treatment in the population. It is useful to conceptualize clinical problems in molecular pharmacoepidemiology by thinking about the mechanism by which genes can affect drug response. Medications with a narrow therapeutic index are good targets for the use of molecular pharmacoepidemiology to improve the use and application of medications. The methodological problems include those of chance and statistical power, confounding, bias, and generalizability. The chapter discusses two primary approaches for gene discovery: candidate gene association studies and genome-wide screens (GWAS)." @default.
- W2912680003 created "2019-02-21" @default.
- W2912680003 creator A5035747289 @default.
- W2912680003 creator A5047049575 @default.
- W2912680003 creator A5074868327 @default.
- W2912680003 date "2013-07-08" @default.
- W2912680003 modified "2023-10-17" @default.
- W2912680003 title "Molecular Pharmacoepidemiology" @default.
- W2912680003 cites W1971983210 @default.
- W2912680003 cites W1980991473 @default.
- W2912680003 cites W1989129581 @default.
- W2912680003 cites W1996323553 @default.
- W2912680003 cites W2032289591 @default.
- W2912680003 cites W2063288921 @default.
- W2912680003 cites W2065435420 @default.
- W2912680003 cites W2076741971 @default.
- W2912680003 cites W2098980155 @default.
- W2912680003 cites W2102697854 @default.
- W2912680003 cites W2104732389 @default.
- W2912680003 cites W2112182958 @default.
- W2912680003 cites W2135451582 @default.
- W2912680003 cites W2151774137 @default.
- W2912680003 cites W2151936813 @default.
- W2912680003 cites W2155033804 @default.
- W2912680003 cites W2164327527 @default.
- W2912680003 cites W2167306345 @default.
- W2912680003 doi "https://doi.org/10.1002/9781118344828.ch14" @default.
- W2912680003 hasPublicationYear "2013" @default.
- W2912680003 type Work @default.
- W2912680003 sameAs 2912680003 @default.
- W2912680003 citedByCount "0" @default.
- W2912680003 crossrefType "other" @default.
- W2912680003 hasAuthorship W2912680003A5035747289 @default.
- W2912680003 hasAuthorship W2912680003A5047049575 @default.
- W2912680003 hasAuthorship W2912680003A5074868327 @default.
- W2912680003 hasConcept C104317684 @default.
- W2912680003 hasConcept C126322002 @default.
- W2912680003 hasConcept C135763542 @default.
- W2912680003 hasConcept C138496976 @default.
- W2912680003 hasConcept C15744967 @default.
- W2912680003 hasConcept C23131810 @default.
- W2912680003 hasConcept C23276603 @default.
- W2912680003 hasConcept C2426938 @default.
- W2912680003 hasConcept C27158222 @default.
- W2912680003 hasConcept C54355233 @default.
- W2912680003 hasConcept C55775858 @default.
- W2912680003 hasConcept C60644358 @default.
- W2912680003 hasConcept C70721500 @default.
- W2912680003 hasConcept C71924100 @default.
- W2912680003 hasConcept C77350462 @default.
- W2912680003 hasConcept C86803240 @default.
- W2912680003 hasConcept C98274493 @default.
- W2912680003 hasConceptScore W2912680003C104317684 @default.
- W2912680003 hasConceptScore W2912680003C126322002 @default.
- W2912680003 hasConceptScore W2912680003C135763542 @default.
- W2912680003 hasConceptScore W2912680003C138496976 @default.
- W2912680003 hasConceptScore W2912680003C15744967 @default.
- W2912680003 hasConceptScore W2912680003C23131810 @default.
- W2912680003 hasConceptScore W2912680003C23276603 @default.
- W2912680003 hasConceptScore W2912680003C2426938 @default.
- W2912680003 hasConceptScore W2912680003C27158222 @default.
- W2912680003 hasConceptScore W2912680003C54355233 @default.
- W2912680003 hasConceptScore W2912680003C55775858 @default.
- W2912680003 hasConceptScore W2912680003C60644358 @default.
- W2912680003 hasConceptScore W2912680003C70721500 @default.
- W2912680003 hasConceptScore W2912680003C71924100 @default.
- W2912680003 hasConceptScore W2912680003C77350462 @default.
- W2912680003 hasConceptScore W2912680003C86803240 @default.
- W2912680003 hasConceptScore W2912680003C98274493 @default.
- W2912680003 hasLocation W29126800031 @default.
- W2912680003 hasOpenAccess W2912680003 @default.
- W2912680003 hasPrimaryLocation W29126800031 @default.
- W2912680003 hasRelatedWork W1566271801 @default.
- W2912680003 hasRelatedWork W2010040257 @default.
- W2912680003 hasRelatedWork W2077726521 @default.
- W2912680003 hasRelatedWork W2160489028 @default.
- W2912680003 hasRelatedWork W2164595809 @default.
- W2912680003 hasRelatedWork W2368205585 @default.
- W2912680003 hasRelatedWork W2765233788 @default.
- W2912680003 hasRelatedWork W3023403406 @default.
- W2912680003 hasRelatedWork W4226206149 @default.
- W2912680003 hasRelatedWork W4243951464 @default.
- W2912680003 isParatext "false" @default.
- W2912680003 isRetracted "false" @default.
- W2912680003 magId "2912680003" @default.
- W2912680003 workType "other" @default.