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- W2912681315 abstract "Aim: The present work provides first-time empirical and molecular interaction evidence to establish the higher biofunctionality of a therapeutic lipid, α-eleostearic acid (ESA), encapsulated in a novel and thoroughly characterized biocompatible nanoemulsion (NE) system (particle size <200 nm). Materials & methods: A novel methodology was employed to fabricate novel formulations of ESA. Molecular biological tools and assays were used to arrive at definite conclusions. Results: The proinflammatory profile was found to be significantly mitigated in the hypersensitized rats administered with the ESA-NE formulation more emphatically as compared with ESA-conventional emulsion in both in vivo and ex vivo models. Conclusion: The novel ESA-NE formulation shows a lot of palpable promise for clinical applications." @default.
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- W2912681315 date "2019-03-01" @default.
- W2912681315 modified "2023-09-26" @default.
- W2912681315 title "A novel nanoformulation of α-eleostearic acid restores molecular pathogenesis of hypersensitivity" @default.
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- W2912681315 doi "https://doi.org/10.2217/nnm-2018-0450" @default.
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