Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912688845> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2912688845 endingPage "228a" @default.
- W2912688845 startingPage "228a" @default.
- W2912688845 abstract "Diffusion of macromolecules and higher-order structures in the crowded interior of cells frequently shows an anomalous behavior with the mean-square displacement (MSD) increasing nonlinearly in time, MSD∝tα. Here we have probed to which extent also larger organelle structures show such an anomalous diffusion and how non-equilibrium contributions affect their diffusional motion [Phys. Rev. E 98, 012406 (2018), in press: Biophys. J. 115 (2018)]. In particular, we have employed single-particle tracking to monitor the motion of tubular junctions in the endoplasmic reticulum (ER) network and of long-lived membrane domains on the ER, called ER exit sites (ERES). Our results show that both, ER junctions and ERES show a distinct anomalous diffusion with a significant anti-correlation of successive step increments that is reminiscent of fractional Brownian motion. Disrupting the microtubule cytoskeleton significantly altered the subdiffusive characteristics of both entities, highlighting that even anomalous diffusion is an actively driven process in living cells. While the diffusion behavior of ER junctions was seen to be directly dependent on the presence and activity of microtubules, ERES were only indirectly affected. ERES therefore can be seen as mobile membrane domains that perform a quasi-one-dimensional random walk on the shivering ER backbone." @default.
- W2912688845 created "2019-02-21" @default.
- W2912688845 creator A5015042130 @default.
- W2912688845 creator A5054742160 @default.
- W2912688845 creator A5082346345 @default.
- W2912688845 date "2019-02-01" @default.
- W2912688845 modified "2023-10-17" @default.
- W2912688845 title "Anomalous Diffusion of Endoplasmic Reticulum Constituents" @default.
- W2912688845 doi "https://doi.org/10.1016/j.bpj.2018.11.1253" @default.
- W2912688845 hasPublicationYear "2019" @default.
- W2912688845 type Work @default.
- W2912688845 sameAs 2912688845 @default.
- W2912688845 citedByCount "0" @default.
- W2912688845 crossrefType "journal-article" @default.
- W2912688845 hasAuthorship W2912688845A5015042130 @default.
- W2912688845 hasAuthorship W2912688845A5054742160 @default.
- W2912688845 hasAuthorship W2912688845A5082346345 @default.
- W2912688845 hasBestOaLocation W29126888451 @default.
- W2912688845 hasConcept C107551265 @default.
- W2912688845 hasConcept C112401455 @default.
- W2912688845 hasConcept C121332964 @default.
- W2912688845 hasConcept C12554922 @default.
- W2912688845 hasConcept C147597530 @default.
- W2912688845 hasConcept C15744967 @default.
- W2912688845 hasConcept C158617107 @default.
- W2912688845 hasConcept C164602753 @default.
- W2912688845 hasConcept C185592680 @default.
- W2912688845 hasConcept C187128312 @default.
- W2912688845 hasConcept C20418707 @default.
- W2912688845 hasConcept C3017618536 @default.
- W2912688845 hasConcept C41008148 @default.
- W2912688845 hasConcept C542102704 @default.
- W2912688845 hasConcept C55493867 @default.
- W2912688845 hasConcept C56739046 @default.
- W2912688845 hasConcept C59593255 @default.
- W2912688845 hasConcept C62520636 @default.
- W2912688845 hasConcept C69357855 @default.
- W2912688845 hasConcept C86803240 @default.
- W2912688845 hasConcept C95444343 @default.
- W2912688845 hasConcept C97355855 @default.
- W2912688845 hasConceptScore W2912688845C107551265 @default.
- W2912688845 hasConceptScore W2912688845C112401455 @default.
- W2912688845 hasConceptScore W2912688845C121332964 @default.
- W2912688845 hasConceptScore W2912688845C12554922 @default.
- W2912688845 hasConceptScore W2912688845C147597530 @default.
- W2912688845 hasConceptScore W2912688845C15744967 @default.
- W2912688845 hasConceptScore W2912688845C158617107 @default.
- W2912688845 hasConceptScore W2912688845C164602753 @default.
- W2912688845 hasConceptScore W2912688845C185592680 @default.
- W2912688845 hasConceptScore W2912688845C187128312 @default.
- W2912688845 hasConceptScore W2912688845C20418707 @default.
- W2912688845 hasConceptScore W2912688845C3017618536 @default.
- W2912688845 hasConceptScore W2912688845C41008148 @default.
- W2912688845 hasConceptScore W2912688845C542102704 @default.
- W2912688845 hasConceptScore W2912688845C55493867 @default.
- W2912688845 hasConceptScore W2912688845C56739046 @default.
- W2912688845 hasConceptScore W2912688845C59593255 @default.
- W2912688845 hasConceptScore W2912688845C62520636 @default.
- W2912688845 hasConceptScore W2912688845C69357855 @default.
- W2912688845 hasConceptScore W2912688845C86803240 @default.
- W2912688845 hasConceptScore W2912688845C95444343 @default.
- W2912688845 hasConceptScore W2912688845C97355855 @default.
- W2912688845 hasIssue "3" @default.
- W2912688845 hasLocation W29126888451 @default.
- W2912688845 hasOpenAccess W2912688845 @default.
- W2912688845 hasPrimaryLocation W29126888451 @default.
- W2912688845 hasRelatedWork W1618612856 @default.
- W2912688845 hasRelatedWork W1681106482 @default.
- W2912688845 hasRelatedWork W1975623965 @default.
- W2912688845 hasRelatedWork W2410032882 @default.
- W2912688845 hasRelatedWork W2763024822 @default.
- W2912688845 hasRelatedWork W2951427856 @default.
- W2912688845 hasRelatedWork W2954931013 @default.
- W2912688845 hasRelatedWork W2963582126 @default.
- W2912688845 hasRelatedWork W4288311933 @default.
- W2912688845 hasRelatedWork W850594699 @default.
- W2912688845 hasVolume "116" @default.
- W2912688845 isParatext "false" @default.
- W2912688845 isRetracted "false" @default.
- W2912688845 magId "2912688845" @default.
- W2912688845 workType "article" @default.