Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912694857> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2912694857 endingPage "454" @default.
- W2912694857 startingPage "448" @default.
- W2912694857 abstract "In a previous study, the modified Marsh and Schnider models respectively showed negatively- and positively-biased predictions in underweight patients. To overcome this drawback, we developed a new pharmacokinetic propofol model-the Choi model-for use in underweight patients. In the present study, we evaluated the predictive performance of the Choi model.Twenty underweight patients undergoing elective surgery received propofol via TCI using the Choi model. The target effect-site concentrations (Ces) of propofol were 2.5, 3, 3.5, 4, 4.5, and 2 μg/mL. Arterial blood samples were obtained at least 10 minutes after achieving pseudo-steady-state. Predicted propofol concentrations with the modified Marsh, Schnider, and Eleveld pharmacokinetic models were obtained by simulation (Asan pump, version 2.1.3; Bionet Co. Ltd., Seoul, Korea). The predictive performance of each model was assessed by calculation of four parameters: inaccuracy, divergence, bias, and wobble.A total of 119 plasma samples were used to determine the predictive performance of the Choi model. Our evaluation showed that the pooled median (95% CI) bias and inaccuracy were 4.0 (-4.2 to 12.2) and 23.9 (17.6-30.3), respectively. The pooled biases and inaccuracies of the modified Marsh, Schnider, and Eleveld models were clinically acceptable. However, the modified Marsh and Eleveld models consistently produced negatively biased predictions in underweight patients. In particular, the Schnider model showed greater inaccuracy at a target Ce ≥ 3 µg/mL.The new propofol pharmacokinetic model (the Choi model) developed for underweight patient showed adequate performance for clinical use." @default.
- W2912694857 created "2019-02-21" @default.
- W2912694857 creator A5015586837 @default.
- W2912694857 creator A5019683266 @default.
- W2912694857 creator A5032026859 @default.
- W2912694857 creator A5050334052 @default.
- W2912694857 creator A5061183717 @default.
- W2912694857 creator A5071194547 @default.
- W2912694857 creator A5074905344 @default.
- W2912694857 creator A5083183967 @default.
- W2912694857 creator A5083294999 @default.
- W2912694857 date "2019-01-28" @default.
- W2912694857 modified "2023-10-01" @default.
- W2912694857 title "Predictive performance of a new pharmacokinetic model for propofol in underweight patients during target-controlled infusion" @default.
- W2912694857 cites W1988207262 @default.
- W2912694857 cites W2017309204 @default.
- W2912694857 cites W2043742363 @default.
- W2912694857 cites W2076009434 @default.
- W2912694857 cites W2080619544 @default.
- W2912694857 cites W2093423304 @default.
- W2912694857 cites W2094375379 @default.
- W2912694857 cites W2115473091 @default.
- W2912694857 cites W2120534719 @default.
- W2912694857 cites W2122171313 @default.
- W2912694857 cites W2126155630 @default.
- W2912694857 cites W2143560345 @default.
- W2912694857 cites W2147377870 @default.
- W2912694857 cites W2168437102 @default.
- W2912694857 cites W2170883480 @default.
- W2912694857 cites W2488700677 @default.
- W2912694857 cites W2551975516 @default.
- W2912694857 cites W2618958745 @default.
- W2912694857 cites W2619309303 @default.
- W2912694857 cites W2791801802 @default.
- W2912694857 cites W2809366481 @default.
- W2912694857 doi "https://doi.org/10.1111/aas.13335" @default.
- W2912694857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30690713" @default.
- W2912694857 hasPublicationYear "2019" @default.
- W2912694857 type Work @default.
- W2912694857 sameAs 2912694857 @default.
- W2912694857 citedByCount "10" @default.
- W2912694857 countsByYear W29126948572019 @default.
- W2912694857 countsByYear W29126948572020 @default.
- W2912694857 countsByYear W29126948572021 @default.
- W2912694857 countsByYear W29126948572022 @default.
- W2912694857 countsByYear W29126948572023 @default.
- W2912694857 crossrefType "journal-article" @default.
- W2912694857 hasAuthorship W2912694857A5015586837 @default.
- W2912694857 hasAuthorship W2912694857A5019683266 @default.
- W2912694857 hasAuthorship W2912694857A5032026859 @default.
- W2912694857 hasAuthorship W2912694857A5050334052 @default.
- W2912694857 hasAuthorship W2912694857A5061183717 @default.
- W2912694857 hasAuthorship W2912694857A5071194547 @default.
- W2912694857 hasAuthorship W2912694857A5074905344 @default.
- W2912694857 hasAuthorship W2912694857A5083183967 @default.
- W2912694857 hasAuthorship W2912694857A5083294999 @default.
- W2912694857 hasConcept C112705442 @default.
- W2912694857 hasConcept C126322002 @default.
- W2912694857 hasConcept C141071460 @default.
- W2912694857 hasConcept C2776277131 @default.
- W2912694857 hasConcept C2780221984 @default.
- W2912694857 hasConcept C2780586474 @default.
- W2912694857 hasConcept C2781121325 @default.
- W2912694857 hasConcept C42219234 @default.
- W2912694857 hasConcept C71924100 @default.
- W2912694857 hasConceptScore W2912694857C112705442 @default.
- W2912694857 hasConceptScore W2912694857C126322002 @default.
- W2912694857 hasConceptScore W2912694857C141071460 @default.
- W2912694857 hasConceptScore W2912694857C2776277131 @default.
- W2912694857 hasConceptScore W2912694857C2780221984 @default.
- W2912694857 hasConceptScore W2912694857C2780586474 @default.
- W2912694857 hasConceptScore W2912694857C2781121325 @default.
- W2912694857 hasConceptScore W2912694857C42219234 @default.
- W2912694857 hasConceptScore W2912694857C71924100 @default.
- W2912694857 hasFunder F4320322103 @default.
- W2912694857 hasIssue "4" @default.
- W2912694857 hasLocation W29126948571 @default.
- W2912694857 hasLocation W29126948572 @default.
- W2912694857 hasOpenAccess W2912694857 @default.
- W2912694857 hasPrimaryLocation W29126948571 @default.
- W2912694857 hasRelatedWork W2096663865 @default.
- W2912694857 hasRelatedWork W2109086070 @default.
- W2912694857 hasRelatedWork W2348152109 @default.
- W2912694857 hasRelatedWork W2350343604 @default.
- W2912694857 hasRelatedWork W2367490127 @default.
- W2912694857 hasRelatedWork W2376033558 @default.
- W2912694857 hasRelatedWork W2391133096 @default.
- W2912694857 hasRelatedWork W2407333079 @default.
- W2912694857 hasRelatedWork W2809366481 @default.
- W2912694857 hasRelatedWork W3150516902 @default.
- W2912694857 hasVolume "63" @default.
- W2912694857 isParatext "false" @default.
- W2912694857 isRetracted "false" @default.
- W2912694857 magId "2912694857" @default.
- W2912694857 workType "article" @default.