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- W2912709632 abstract "The flower buds of Lonicera macranthoides (Shan Yin-Hua), represent an important traditional Chinese medicine and food ingredient. A phytochemical investigation of the 70% EtOH extract of the flower buds of L. macranthoides resulted in the isolation of 12 triterpenoids (1–12), including two new ursane-type nortriterpenes, 2α, 24-dihydroxy-23-nor-ursolic acid (1) and 2α, 4α-dihydroxy-23-nor-ursolic acid (2). Their structures were established by multiple spectroscopic methods and comparison with literature data. All isolated compounds were evaluated for their anti-inflammatory effects in LPS-activated RAW264.7 cells. Compounds 1 and 2 exhibited inhibitory effects on iNOS at the concentration of 30 μmol·L−1." @default.
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- W2912709632 date "2019-01-01" @default.
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- W2912709632 title "Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities" @default.
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- W2912709632 doi "https://doi.org/10.1016/s1875-5364(19)30006-8" @default.
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