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- W2912710143 endingPage "232596711882440" @default.
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- W2912710143 abstract "Although anterior cruciate ligament (ACL) tears have received the most attention, the medial collateral ligament (MCL) is thought to be the most commonly injured knee ligament overall. The lateral collateral ligament (LCL) and posterior collateral ligament (PCL) are less frequently compromised but can be involved in severe multiligament injuries. The paucity of information on the native properties of these ligaments in the pediatric population hinders the overall optimization of treatment for these injuries.To characterize the mechanical and microstructural properties of pediatric MCLs, LCLs, and PCLs using a rare cadaveric cohort (mean age, 9.2 years).Descriptive laboratory study.MCLs, LCLs, and PCLs were harvested from 5 fresh-frozen pediatric knee specimens (3 male, 2 female) and were subjected to a tensile loading protocol. A subset of contralateral tissues from a single donor was analyzed using bright-field, polarized light, and transmission electron microscopy to measure collagen fiber morphology.The pediatric MCL exhibited values for ultimate stress (11.7 ± 6.7 MPa), ultimate strain (18.2% ± 6.8%), and the Young modulus (93.7 ± 56.5 MPa) that were similar to values for the LCL (11.4 ± 11.5 MPa, 27.7% ± 12.9%, and 64.4 ± 76.6 MPa, respectively). The PCL demonstrated decreased ultimate stress (4.2 ± 1.8 MPa), increased ultimate strain (28.8% ± 11.9%), and a decreased Young modulus (19.8 ± 10.4 MPa) when compared with the MCL and LCL. All 3 ligaments had similar mean crimp wavelengths (MCL, 32.8 ± 3.6 µm; LCL, 27.2 ± 3.5 µm; PCL, 25.8 ± 3.5 µm) and collagen fibril diameters (MCL, 88.0 ± 26.0 nm; LCL, 93.3 ± 34.6 nm; PCL, 90.9 ± 34.0 nm); however, the fibril distribution profiles exhibited different modalities.The pediatric MCL and LCL possessed similar mechanical properties, while the pediatric PCL was weaker but capable of withstanding higher amounts of strain. All 3 of these pediatric structures were weaker than what has been reported in studies with adult cohorts.Results from this study can be considered preliminary mechanical and microstructural data for healthy pediatric collateral and posterior cruciate ligaments that can be used to guide further laboratory and clinical research." @default.
- W2912710143 created "2019-02-21" @default.
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- W2912710143 date "2019-02-01" @default.
- W2912710143 modified "2023-10-16" @default.
- W2912710143 title "Mechanical and Microstructural Properties of Native Pediatric Posterior Cruciate and Collateral Ligaments" @default.
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- W2912710143 cites W1964572505 @default.
- W2912710143 cites W1973618869 @default.
- W2912710143 cites W1976895140 @default.
- W2912710143 cites W1978468696 @default.
- W2912710143 cites W1980118597 @default.
- W2912710143 cites W1985433369 @default.
- W2912710143 cites W1995171880 @default.
- W2912710143 cites W2001251903 @default.
- W2912710143 cites W2003633565 @default.
- W2912710143 cites W2005759861 @default.
- W2912710143 cites W2006683353 @default.
- W2912710143 cites W2007131363 @default.
- W2912710143 cites W2009024551 @default.
- W2912710143 cites W2009468495 @default.
- W2912710143 cites W2012736920 @default.
- W2912710143 cites W2021175216 @default.
- W2912710143 cites W2029582946 @default.
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- W2912710143 cites W2058107094 @default.
- W2912710143 cites W2071609694 @default.
- W2912710143 cites W2075014244 @default.
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- W2912710143 cites W2153292834 @default.
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- W2912710143 doi "https://doi.org/10.1177/2325967118824400" @default.
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