FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912763185> ?p ?o ?g. }

• W2912763185 endingPage "42" @default.
• W2912763185 startingPage "35" @default.
• W2912763185 abstract "Rates of asthma in Jordan have been doubled in the past decade, but this increased prevalence was not met with improved asthma control protocols. The aim of the present study was to assess whether there was any significant association between the level of asthma control and certain single-nucleotide polymorphisms (SNPs) in five genes: (ADRB2; rs1042713 and rs1042714), (CRHR1; rs1876828, rs242939, and rs242941), (STIP1; rs2236647), (ADH5, rs1154400), and (ARG1; rs2781659). These SNPs were selected based on their involvement in enzymes and receptors that are related to asthma pathways and subsequent response to medication and based on a high degree of linkage disequilibrium.A cross-sectional genetic association study was conducted from June 2016 to June 2017 in the two major hospitals in Jordan. The present study involved sampling from adult asthmatic patients of Arab descent who were selected from two phenotypic groups, ie, controlled and uncontrolled asthma. The blood samples and medical data were collected from the participants. DNA samples were extracted, quantified, and genotyped according to standard operating procedure. Allelic and haplotypic analyses were performed using the Haploview®.A total of 245 Arab asthmatic patients were enrolled in this study. Genotyping analysis revealed that the two SNPs (rs1042713 and rs1042714) in ADRB2 gene, along with their related haplotypes, were nominally significantly associated with asthma control in the Jordanian population. The A-allele of rs1042713 and the C-allele of rs1042714 were more common in the uncontrolled asthma group than in the controlled asthma group (P=0.048 and P=0.017, respectively).This was the first study that identified the nominal significant association between the level of asthma control and genetic variants in ADRB2 gene in Arab population. Further studies in other Arab region with larger sample size are recommended to confirm the relationship." @default.
• W2912763185 created "2019-02-21" @default.
• W2912763185 creator A5067558362 @default.
• W2912763185 creator A5078212433 @default.
• W2912763185 creator A5079453950 @default.
• W2912763185 creator A5085557672 @default.
• W2912763185 creator A5086300210 @default.
• W2912763185 date "2019-01-01" @default.
• W2912763185 modified "2023-10-16" @default.
• W2912763185 title "<p>Association of genetic variants with level of asthma control in the Arab population</p>" @default.
• W2912763185 cites W105427924 @default.
• W2912763185 cites W1966466376 @default.
• W2912763185 cites W1967969693 @default.
• W2912763185 cites W1975914622 @default.
• W2912763185 cites W1985781468 @default.
• W2912763185 cites W2001587426 @default.
• W2912763185 cites W2004028427 @default.
• W2912763185 cites W2013003176 @default.
• W2912763185 cites W2023745323 @default.
• W2912763185 cites W2051117533 @default.
• W2912763185 cites W2065515544 @default.
• W2912763185 cites W2067785832 @default.
• W2912763185 cites W2076239743 @default.
• W2912763185 cites W2080462575 @default.
• W2912763185 cites W2084785963 @default.
• W2912763185 cites W2087574085 @default.
• W2912763185 cites W2092693604 @default.
• W2912763185 cites W2108449402 @default.
• W2912763185 cites W2113096218 @default.
• W2912763185 cites W2126279305 @default.
• W2912763185 cites W2130866682 @default.
• W2912763185 cites W2133831418 @default.
• W2912763185 cites W2134436842 @default.
• W2912763185 cites W2139024308 @default.
• W2912763185 cites W2142356382 @default.
• W2912763185 cites W2144438866 @default.
• W2912763185 cites W2145322825 @default.
• W2912763185 cites W2152785448 @default.
• W2912763185 cites W2159684987 @default.
• W2912763185 cites W2177680908 @default.
• W2912763185 cites W2202158545 @default.
• W2912763185 cites W2287321481 @default.
• W2912763185 cites W2315439669 @default.
• W2912763185 cites W2558209724 @default.
• W2912763185 cites W2571026257 @default.
• W2912763185 cites W2592258477 @default.
• W2912763185 cites W2616424562 @default.
• W2912763185 cites W2744471011 @default.
• W2912763185 cites W2794017767 @default.
• W2912763185 cites W2801581675 @default.
• W2912763185 cites W3010813893 @default.
• W2912763185 cites W322258661 @default.
• W2912763185 doi "https://doi.org/10.2147/jaa.s186252" @default.
• W2912763185 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6350652" @default.
• W2912763185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30774389" @default.
• W2912763185 hasPublicationYear "2019" @default.
• W2912763185 type Work @default.
• W2912763185 sameAs 2912763185 @default.
• W2912763185 citedByCount "7" @default.
• W2912763185 countsByYear W29127631852019 @default.
• W2912763185 countsByYear W29127631852020 @default.
• W2912763185 countsByYear W29127631852021 @default.
• W2912763185 countsByYear W29127631852023 @default.
• W2912763185 crossrefType "journal-article" @default.
• W2912763185 hasAuthorship W2912763185A5067558362 @default.
• W2912763185 hasAuthorship W2912763185A5078212433 @default.
• W2912763185 hasAuthorship W2912763185A5079453950 @default.
• W2912763185 hasAuthorship W2912763185A5085557672 @default.
• W2912763185 hasAuthorship W2912763185A5086300210 @default.
• W2912763185 hasBestOaLocation W29127631851 @default.
• W2912763185 hasConcept C104317684 @default.
• W2912763185 hasConcept C126322002 @default.
• W2912763185 hasConcept C135763542 @default.
• W2912763185 hasConcept C153209595 @default.
• W2912763185 hasConcept C180754005 @default.
• W2912763185 hasConcept C186413461 @default.
• W2912763185 hasConcept C197754878 @default.
• W2912763185 hasConcept C2776042228 @default.
• W2912763185 hasConcept C2908647359 @default.
• W2912763185 hasConcept C31467283 @default.
• W2912763185 hasConcept C35605836 @default.
• W2912763185 hasConcept C37463918 @default.
• W2912763185 hasConcept C54355233 @default.
• W2912763185 hasConcept C71924100 @default.
• W2912763185 hasConcept C86803240 @default.
• W2912763185 hasConcept C99454951 @default.
• W2912763185 hasConceptScore W2912763185C104317684 @default.
• W2912763185 hasConceptScore W2912763185C126322002 @default.
• W2912763185 hasConceptScore W2912763185C135763542 @default.
• W2912763185 hasConceptScore W2912763185C153209595 @default.
• W2912763185 hasConceptScore W2912763185C180754005 @default.
• W2912763185 hasConceptScore W2912763185C186413461 @default.
• W2912763185 hasConceptScore W2912763185C197754878 @default.
• W2912763185 hasConceptScore W2912763185C2776042228 @default.
• W2912763185 hasConceptScore W2912763185C2908647359 @default.
• W2912763185 hasConceptScore W2912763185C31467283 @default.
• W2912763185 hasConceptScore W2912763185C35605836 @default.
• W2912763185 hasConceptScore W2912763185C37463918 @default.

• next