FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912763859> ?p ?o ?g. }

• W2912763859 endingPage "187" @default.
• W2912763859 startingPage "178" @default.
• W2912763859 abstract "Constructing intracellular degradable drug delivery vehicles is critical to fully exert the function of loaded drugs. Considering the poly (amino acid) is sensitively degradable to acid and enzyme which indwell in the mature lysosome, we here presented the poly(amino acid) capsules constructed by the synthetic poly(amino acid), (poly-glutamic acid, PGA and poly-ornithine, POR). The fabrication of Dox loaded poly (amino acid) capsules was demonstrated, and was thoroughly characterized by various techniques, including Zetasizer, SEM, TEM, fluorescent microscopy, and confocal laser scan microscopy. By controlling fabrication process, we tuned the carriers with different physical properties (charges and stiffness). Then, we thoroughly investigated the effects of these properties on the intracellular uptake and anti-cancer abilities of various carriers@Dox. In addition, the degradability of poly(amino acid) capsules was studied to reveal the release profiles of the carriers with or without templates from the side aspect. We found the positively charged and stiffer carriers mainly contributed to the cellular uptake process and amount, while both the uptake amount and degradability of the endocytosed carriers@Dox played a critical role on the cytotoxicity. We believe the findings here could pave the way for designing poly(amino acid) capsules or other degradable polymers based on poly(amino acid) as the drug delivery vehicles." @default.
• W2912763859 created "2019-02-21" @default.
• W2912763859 creator A5006356165 @default.
• W2912763859 creator A5008506855 @default.
• W2912763859 creator A5008942476 @default.
• W2912763859 creator A5022499603 @default.
• W2912763859 creator A5061933095 @default.
• W2912763859 creator A5066220846 @default.
• W2912763859 creator A5066714426 @default.
• W2912763859 creator A5083694400 @default.
• W2912763859 creator A5085603429 @default.
• W2912763859 date "2019-05-01" @default.
• W2912763859 modified "2023-09-27" @default.
• W2912763859 title "The construction and effect of physical properties on intracellular drug delivery of poly(amino acid) capsules" @default.
• W2912763859 cites W1667192877 @default.
• W2912763859 cites W1964746125 @default.
• W2912763859 cites W1978698417 @default.
• W2912763859 cites W1990947889 @default.
• W2912763859 cites W2002879789 @default.
• W2912763859 cites W2020627417 @default.
• W2912763859 cites W2022854787 @default.
• W2912763859 cites W2025165285 @default.
• W2912763859 cites W2029851331 @default.
• W2912763859 cites W2030574023 @default.
• W2912763859 cites W2038914834 @default.
• W2912763859 cites W2046565260 @default.
• W2912763859 cites W2048878719 @default.
• W2912763859 cites W2050297071 @default.
• W2912763859 cites W2057760381 @default.
• W2912763859 cites W2059298390 @default.
• W2912763859 cites W2060558744 @default.
• W2912763859 cites W2064093384 @default.
• W2912763859 cites W2088732135 @default.
• W2912763859 cites W2088925027 @default.
• W2912763859 cites W2094589089 @default.
• W2912763859 cites W2100090013 @default.
• W2912763859 cites W2108615682 @default.
• W2912763859 cites W2119973415 @default.
• W2912763859 cites W2148358706 @default.
• W2912763859 cites W2163428285 @default.
• W2912763859 cites W2165210975 @default.
• W2912763859 cites W2312767790 @default.
• W2912763859 cites W2317055602 @default.
• W2912763859 cites W2320026384 @default.
• W2912763859 cites W2323007809 @default.
• W2912763859 cites W2333282498 @default.
• W2912763859 cites W2334035176 @default.
• W2912763859 cites W2513369486 @default.
• W2912763859 cites W2527943384 @default.
• W2912763859 cites W2566788774 @default.
• W2912763859 cites W257094742 @default.
• W2912763859 cites W2917837889 @default.
• W2912763859 cites W4235614466 @default.
• W2912763859 cites W805519689 @default.
• W2912763859 doi "https://doi.org/10.1016/j.colsurfb.2019.01.061" @default.
• W2912763859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30738324" @default.
• W2912763859 hasPublicationYear "2019" @default.
• W2912763859 type Work @default.
• W2912763859 sameAs 2912763859 @default.
• W2912763859 citedByCount "6" @default.
• W2912763859 countsByYear W29127638592019 @default.
• W2912763859 countsByYear W29127638592021 @default.
• W2912763859 countsByYear W29127638592022 @default.
• W2912763859 countsByYear W29127638592023 @default.
• W2912763859 crossrefType "journal-article" @default.
• W2912763859 hasAuthorship W2912763859A5006356165 @default.
• W2912763859 hasAuthorship W2912763859A5008506855 @default.
• W2912763859 hasAuthorship W2912763859A5008942476 @default.
• W2912763859 hasAuthorship W2912763859A5022499603 @default.
• W2912763859 hasAuthorship W2912763859A5061933095 @default.
• W2912763859 hasAuthorship W2912763859A5066220846 @default.
• W2912763859 hasAuthorship W2912763859A5066714426 @default.
• W2912763859 hasAuthorship W2912763859A5083694400 @default.
• W2912763859 hasAuthorship W2912763859A5085603429 @default.
• W2912763859 hasConcept C109316439 @default.
• W2912763859 hasConcept C12554922 @default.
• W2912763859 hasConcept C13245373 @default.
• W2912763859 hasConcept C171250308 @default.
• W2912763859 hasConcept C178790620 @default.
• W2912763859 hasConcept C181199279 @default.
• W2912763859 hasConcept C185592680 @default.
• W2912763859 hasConcept C192562407 @default.
• W2912763859 hasConcept C202751555 @default.
• W2912763859 hasConcept C21951064 @default.
• W2912763859 hasConcept C2776207055 @default.
• W2912763859 hasConcept C2778740566 @default.
• W2912763859 hasConcept C2779178360 @default.
• W2912763859 hasConcept C2779820397 @default.
• W2912763859 hasConcept C2780216420 @default.
• W2912763859 hasConcept C515207424 @default.
• W2912763859 hasConcept C521977710 @default.
• W2912763859 hasConcept C55493867 @default.
• W2912763859 hasConcept C79879829 @default.
• W2912763859 hasConcept C86803240 @default.
• W2912763859 hasConcept C95444343 @default.
• W2912763859 hasConceptScore W2912763859C109316439 @default.
• W2912763859 hasConceptScore W2912763859C12554922 @default.
• W2912763859 hasConceptScore W2912763859C13245373 @default.

• next