FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912782735> ?p ?o ?g. }

• W2912782735 endingPage "e000950" @default.
• W2912782735 startingPage "e000950" @default.
• W2912782735 abstract "Objective To examine the clinical significance and prognostic value of an early rapid rise in heart rate (RR-HR) in asymptomatic patients with moderate or severe aortic stenosis (AS). Methods We retrospectively assessed the prospectively collected data from 306 patients (age 65±12 years, 33% women) with moderate (n=204) or severe AS (n=102) with a median follow-up of 25 months (mean 34.9±34.6 months). All had echocardiography and modified Bruce exercise treadmill tests (ETT). RR-HR was defined as achieving 85% target HR or ≥50% increase from baseline in the first 6 min. The outcome measures were revealed symptoms during ETT, aortic valve replacement (AVR) and all-cause mortality. Results RR-HR occurred in 77 (25%) and 64% developed revealed symptoms (postive predictive value 64% and negative predictive value 84%). On univariate Cox regression analyses in patients with severe AS, RR-HR was associated with AVR (HR 3.32, 95% CI 2.03 to 5.45, p<0.001) but not with all-cause mortality (HR 0.04, 95% CI 0.13 to 9.21, p=0.798). In patients with moderate AS, RR-HR was associated with all-cause mortality (HR 2.67, 95% CI 1.09 to 6.56, p=0.032), but not with AVR (HR 1.35, 95% CI 0.92 to 1.98, p=0.127). These associations remained significant in multivariate Cox regression analyses after adjustment for age, sex, hypertension, coronary artery disease, abnormal blood pressure response, Doppler stroke volume and mean pressure gradient (both p<0.001). Conclusions RR-HR was associated with the development of revealed symptoms. It predicted revealed symptoms on serial ETT, AVR in severe AS and all-cause mortality in moderate AS. RR-HR may be a useful new measure to define risk in AS." @default.
• W2912782735 created "2019-02-21" @default.
• W2912782735 creator A5004157739 @default.
• W2912782735 creator A5042153849 @default.
• W2912782735 creator A5082544361 @default.
• W2912782735 creator A5084775166 @default.
• W2912782735 date "2019-01-01" @default.
• W2912782735 modified "2023-09-27" @default.
• W2912782735 title "Rapid early rise in heart rate on treadmill exercise in patients with asymptomatic moderate or severe aortic stenosis: a new prognostic marker?" @default.
• W2912782735 cites W1948348644 @default.
• W2912782735 cites W1965806808 @default.
• W2912782735 cites W1965887353 @default.
• W2912782735 cites W1978818092 @default.
• W2912782735 cites W1989586445 @default.
• W2912782735 cites W1990737135 @default.
• W2912782735 cites W2004844047 @default.
• W2912782735 cites W2016448573 @default.
• W2912782735 cites W2066203395 @default.
• W2912782735 cites W2066878784 @default.
• W2912782735 cites W2067504286 @default.
• W2912782735 cites W2108314801 @default.
• W2912782735 cites W2112050863 @default.
• W2912782735 cites W2118032401 @default.
• W2912782735 cites W2123954317 @default.
• W2912782735 cites W2125579882 @default.
• W2912782735 cites W2137038354 @default.
• W2912782735 cites W2142021694 @default.
• W2912782735 cites W2153568907 @default.
• W2912782735 cites W2157875984 @default.
• W2912782735 cites W2266929541 @default.
• W2912782735 cites W2333829416 @default.
• W2912782735 cites W2588068022 @default.
• W2912782735 cites W2751630023 @default.
• W2912782735 cites W2797497081 @default.
• W2912782735 cites W2912662387 @default.
• W2912782735 cites W4239414585 @default.
• W2912782735 cites W87766410 @default.
• W2912782735 doi "https://doi.org/10.1136/openhrt-2018-000950" @default.
• W2912782735 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6361371" @default.
• W2912782735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30815268" @default.
• W2912782735 hasPublicationYear "2019" @default.
• W2912782735 type Work @default.
• W2912782735 sameAs 2912782735 @default.
• W2912782735 citedByCount "9" @default.
• W2912782735 countsByYear W29127827352019 @default.
• W2912782735 countsByYear W29127827352020 @default.
• W2912782735 countsByYear W29127827352021 @default.
• W2912782735 countsByYear W29127827352022 @default.
• W2912782735 crossrefType "journal-article" @default.
• W2912782735 hasAuthorship W2912782735A5004157739 @default.
• W2912782735 hasAuthorship W2912782735A5042153849 @default.
• W2912782735 hasAuthorship W2912782735A5082544361 @default.
• W2912782735 hasAuthorship W2912782735A5084775166 @default.
• W2912782735 hasBestOaLocation W29127827351 @default.
• W2912782735 hasConcept C126322002 @default.
• W2912782735 hasConcept C127413603 @default.
• W2912782735 hasConcept C141071460 @default.
• W2912782735 hasConcept C144301174 @default.
• W2912782735 hasConcept C164705383 @default.
• W2912782735 hasConcept C2776570981 @default.
• W2912782735 hasConcept C2777910003 @default.
• W2912782735 hasConcept C2777953023 @default.
• W2912782735 hasConcept C2778213512 @default.
• W2912782735 hasConcept C2780007028 @default.
• W2912782735 hasConcept C2780645631 @default.
• W2912782735 hasConcept C2781414266 @default.
• W2912782735 hasConcept C38180746 @default.
• W2912782735 hasConcept C50382708 @default.
• W2912782735 hasConcept C71924100 @default.
• W2912782735 hasConcept C78519656 @default.
• W2912782735 hasConcept C84393581 @default.
• W2912782735 hasConceptScore W2912782735C126322002 @default.
• W2912782735 hasConceptScore W2912782735C127413603 @default.
• W2912782735 hasConceptScore W2912782735C141071460 @default.
• W2912782735 hasConceptScore W2912782735C144301174 @default.
• W2912782735 hasConceptScore W2912782735C164705383 @default.
• W2912782735 hasConceptScore W2912782735C2776570981 @default.
• W2912782735 hasConceptScore W2912782735C2777910003 @default.
• W2912782735 hasConceptScore W2912782735C2777953023 @default.
• W2912782735 hasConceptScore W2912782735C2778213512 @default.
• W2912782735 hasConceptScore W2912782735C2780007028 @default.
• W2912782735 hasConceptScore W2912782735C2780645631 @default.
• W2912782735 hasConceptScore W2912782735C2781414266 @default.
• W2912782735 hasConceptScore W2912782735C38180746 @default.
• W2912782735 hasConceptScore W2912782735C50382708 @default.
• W2912782735 hasConceptScore W2912782735C71924100 @default.
• W2912782735 hasConceptScore W2912782735C78519656 @default.
• W2912782735 hasConceptScore W2912782735C84393581 @default.
• W2912782735 hasIssue "1" @default.
• W2912782735 hasLocation W29127827351 @default.
• W2912782735 hasLocation W29127827352 @default.
• W2912782735 hasLocation W29127827353 @default.
• W2912782735 hasOpenAccess W2912782735 @default.
• W2912782735 hasPrimaryLocation W29127827351 @default.
• W2912782735 hasRelatedWork W2021480092 @default.
• W2912782735 hasRelatedWork W2048328845 @default.
• W2912782735 hasRelatedWork W2123091817 @default.
• W2912782735 hasRelatedWork W2298053629 @default.

• next