Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912782806> ?p ?o ?g. }
- W2912782806 endingPage "165373" @default.
- W2912782806 startingPage "165373" @default.
- W2912782806 abstract "The most common cause of intrauterine growth restriction (IUGR) in the developed world is placental insufficiency, a concept often used synonymously with reduced utero-placental and umbilical blood flows. However, placental insufficiency and IUGR are associated with complex, coordinated and highly regulated changes in placental signaling and nutrient transport including inhibition of insulin and mTOR signaling and down-regulation of specific amino acid transporters, Na+/K+-ATPase, the Na+/H+-exchanger, folate and lactate transporters. In contrast, placental glucose transport capacity is unaltered and Ca2+-ATPase activity and the expression of proteins involved in placental lipid transport are increased in IUGR. These findings are not entirely consistent with the traditional view that the placenta is dysfunctional in IUGR, but rather suggest that the placenta adapts to reduce fetal growth in response to an inability of the mother to allocate resources to the fetus. This new model has implications for the understanding of the mechanisms underpinning IUGR and for the development of intervention strategies." @default.
- W2912782806 created "2019-02-21" @default.
- W2912782806 creator A5008660282 @default.
- W2912782806 creator A5068691304 @default.
- W2912782806 date "2020-02-01" @default.
- W2912782806 modified "2023-10-15" @default.
- W2912782806 title "Complex, coordinated and highly regulated changes in placental signaling and nutrient transport capacity in IUGR" @default.
- W2912782806 cites W1463783763 @default.
- W2912782806 cites W1488559297 @default.
- W2912782806 cites W1494032084 @default.
- W2912782806 cites W1501164720 @default.
- W2912782806 cites W1511830885 @default.
- W2912782806 cites W1542112251 @default.
- W2912782806 cites W1569242858 @default.
- W2912782806 cites W1585246110 @default.
- W2912782806 cites W1603980865 @default.
- W2912782806 cites W1708690454 @default.
- W2912782806 cites W1761670585 @default.
- W2912782806 cites W1866530546 @default.
- W2912782806 cites W1874090210 @default.
- W2912782806 cites W1882907636 @default.
- W2912782806 cites W1964301276 @default.
- W2912782806 cites W1964675126 @default.
- W2912782806 cites W1964880900 @default.
- W2912782806 cites W1965686949 @default.
- W2912782806 cites W1965976637 @default.
- W2912782806 cites W1967378408 @default.
- W2912782806 cites W1968215122 @default.
- W2912782806 cites W1968703258 @default.
- W2912782806 cites W1971524709 @default.
- W2912782806 cites W1971774838 @default.
- W2912782806 cites W1973061822 @default.
- W2912782806 cites W1974239834 @default.
- W2912782806 cites W1974323903 @default.
- W2912782806 cites W1975164000 @default.
- W2912782806 cites W1977220779 @default.
- W2912782806 cites W1979943253 @default.
- W2912782806 cites W1980178343 @default.
- W2912782806 cites W1980195461 @default.
- W2912782806 cites W1986520434 @default.
- W2912782806 cites W1991691574 @default.
- W2912782806 cites W1991922220 @default.
- W2912782806 cites W1992170852 @default.
- W2912782806 cites W1993172420 @default.
- W2912782806 cites W1993194232 @default.
- W2912782806 cites W1993368282 @default.
- W2912782806 cites W1993794913 @default.
- W2912782806 cites W1993909589 @default.
- W2912782806 cites W1995806596 @default.
- W2912782806 cites W1996022970 @default.
- W2912782806 cites W1999065094 @default.
- W2912782806 cites W1999946965 @default.
- W2912782806 cites W2000429863 @default.
- W2912782806 cites W2001849513 @default.
- W2912782806 cites W2001867509 @default.
- W2912782806 cites W2002763203 @default.
- W2912782806 cites W2004097699 @default.
- W2912782806 cites W2004382470 @default.
- W2912782806 cites W2004601478 @default.
- W2912782806 cites W2004863456 @default.
- W2912782806 cites W2006011862 @default.
- W2912782806 cites W2006540204 @default.
- W2912782806 cites W2006601239 @default.
- W2912782806 cites W2006846354 @default.
- W2912782806 cites W2007042696 @default.
- W2912782806 cites W2007721877 @default.
- W2912782806 cites W2008244265 @default.
- W2912782806 cites W2011785882 @default.
- W2912782806 cites W2011795533 @default.
- W2912782806 cites W2012207297 @default.
- W2912782806 cites W2016673365 @default.
- W2912782806 cites W2016900818 @default.
- W2912782806 cites W2017949036 @default.
- W2912782806 cites W2018891761 @default.
- W2912782806 cites W2025267820 @default.
- W2912782806 cites W2030306871 @default.
- W2912782806 cites W2031327135 @default.
- W2912782806 cites W2032226016 @default.
- W2912782806 cites W2033204507 @default.
- W2912782806 cites W2033408373 @default.
- W2912782806 cites W2034161006 @default.
- W2912782806 cites W2035863659 @default.
- W2912782806 cites W2036570625 @default.
- W2912782806 cites W2037594642 @default.
- W2912782806 cites W2038343657 @default.
- W2912782806 cites W2038440449 @default.
- W2912782806 cites W2039792651 @default.
- W2912782806 cites W2040336914 @default.
- W2912782806 cites W2040639535 @default.
- W2912782806 cites W2041519751 @default.
- W2912782806 cites W2041628249 @default.
- W2912782806 cites W2044440239 @default.
- W2912782806 cites W2044451058 @default.
- W2912782806 cites W2044758144 @default.
- W2912782806 cites W2044786978 @default.
- W2912782806 cites W2050720833 @default.
- W2912782806 cites W2051855513 @default.
- W2912782806 cites W2051877078 @default.