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- W2912783102 abstract "The total synthesis of majusculamide D (MJS-D) is described, a lipopentapeptide originally isolated from Lyngbya majuscula and reisolated from a Moorea sp. MJS-D possesses selective and potent cancer cell toxicity. A scalable and convergent strategy with a minimal number of purifications produced significant quantities of MJM-D for in vivo evaluations. The absolute configuration of the 1,3-dimethyl-octanamide motif was determined by synthesis of this fragment via ZACA chemistry." @default.
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- W2912783102 date "2019-01-23" @default.
- W2912783102 modified "2023-10-17" @default.
- W2912783102 title "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from <i>Moorea sp.</i>" @default.
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- W2912783102 doi "https://doi.org/10.1021/acs.orglett.8b04050" @default.
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