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• W2912784825 abstract "Mathematical reasoning is central to everyday life. Lesion data and functional MRI studies suggest that even simple arithmetic involves the coordination of multiple spatially diverse brain regions, but to date, math processing has not been well characterized using direct brain recordings, especially outside of the parietal cortex. To address this, we utilized an unparalleled data set of 310 subjects implanted with intracranial electrodes to investigate the spatial and temporal dynamics of arithmetic reasoning. Our data support the importance of regions previously implicated in numerosity such as the superior parietal lobule and intraparietal sulcus. However, we also identify contributions to arithmetic processing from regions such as the entorhinal cortex and temporal pole. Using the excellent bihemispheric coverage afforded by our data set and the precise temporal resolution of intracranial recordings, we characterize in detail the spatial and temporal characteristics of an arithmetic processing network, quantifying subtle hemispheric differences for selected regions. We also examine how activity in these regions predicts arithmetic ability and look for gender differences in the pattern of network activation. Our findings further define the complex network of regions involved in human arithmetical reasoning." @default.
• W2912784825 created "2019-02-21" @default.
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• W2912784825 date "2019-02-06" @default.
• W2912784825 modified "2023-09-30" @default.
• W2912784825 title "Intracranial EEG reveals bihemispheric parietal and extra parietal brain networks supporting mental arithmetic" @default.
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• W2912784825 doi "https://doi.org/10.1101/542142" @default.
• W2912784825 hasPublicationYear "2019" @default.
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