FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912787197> ?p ?o ?g. }

• W2912787197 endingPage "7" @default.
• W2912787197 startingPage "1" @default.
• W2912787197 abstract "Oxidized low-density lipoproteins (oxLDL) play a pivotal role in the etiopathogenesis of atherosclerosis through the activation of inflammatory signaling events eventually leading to endothelial dysfunction and senescence. In the present work, we investigated the effects of indicaxanthin, a bioavailable, redox-modulating phytochemical from Opuntia ficus indica fruits, with anti-inflammatory activity, against oxLDL-induced endothelial dysfunction. Human umbilical vein cord cells (HUVEC) were stimulated with human oxLDL, and the effects of indicaxanthin were evaluated in a range between 5 and 20 μ M, consistent with its plasma level after a fruit meal (7 μ M). Pretreatment with indicaxanthin significantly and concentration-dependently inhibited oxLDL-induced cytotoxicity; ICAM-1, VCAM-1, and ELAM-1 increase; and ABC-A1 decrease of both protein and mRNA levels. From a mechanistic perspective, we also provided evidence that the protective effects of indicaxanthin were redox-dependent and related to the pigment efficacy to inhibit NF- κ B transcriptional activity. In conclusion, here we demonstrate indicaxanthin as a novel, dietary phytochemical, able to exert significant protective vascular effects in vitro , at nutritionally relevant concentrations." @default.
• W2912787197 created "2019-02-21" @default.
• W2912787197 creator A5005608086 @default.
• W2912787197 creator A5012386440 @default.
• W2912787197 creator A5024098116 @default.
• W2912787197 creator A5048901530 @default.
• W2912787197 creator A5052991414 @default.
• W2912787197 creator A5057723638 @default.
• W2912787197 date "2019-02-18" @default.
• W2912787197 modified "2023-10-12" @default.
• W2912787197 title "Indicaxanthin from <i>Opuntia ficus indica</i> (L. Mill) Inhibits Oxidized LDL-Mediated Human Endothelial Cell Dysfunction through Inhibition of NF-<i>κ</i>B Activation" @default.
• W2912787197 cites W1901285641 @default.
• W2912787197 cites W1965000046 @default.
• W2912787197 cites W2029810011 @default.
• W2912787197 cites W2038885723 @default.
• W2912787197 cites W2040873123 @default.
• W2912787197 cites W2041377319 @default.
• W2912787197 cites W2055177094 @default.
• W2912787197 cites W2067168138 @default.
• W2912787197 cites W2084798714 @default.
• W2912787197 cites W2091476343 @default.
• W2912787197 cites W2098190175 @default.
• W2912787197 cites W2117328824 @default.
• W2912787197 cites W2128635872 @default.
• W2912787197 cites W2144290541 @default.
• W2912787197 cites W2145807969 @default.
• W2912787197 cites W2171889873 @default.
• W2912787197 cites W2211999579 @default.
• W2912787197 cites W2212641796 @default.
• W2912787197 cites W2403798563 @default.
• W2912787197 cites W2406695003 @default.
• W2912787197 cites W2565562363 @default.
• W2912787197 cites W2586704547 @default.
• W2912787197 cites W2793853755 @default.
• W2912787197 cites W2806000147 @default.
• W2912787197 cites W2809383046 @default.
• W2912787197 cites W4293247451 @default.
• W2912787197 doi "https://doi.org/10.1155/2019/3457846" @default.
• W2912787197 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6398026" @default.
• W2912787197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30911345" @default.
• W2912787197 hasPublicationYear "2019" @default.
• W2912787197 type Work @default.
• W2912787197 sameAs 2912787197 @default.
• W2912787197 citedByCount "14" @default.
• W2912787197 countsByYear W29127871972019 @default.
• W2912787197 countsByYear W29127871972020 @default.
• W2912787197 countsByYear W29127871972021 @default.
• W2912787197 countsByYear W29127871972022 @default.
• W2912787197 countsByYear W29127871972023 @default.
• W2912787197 crossrefType "journal-article" @default.
• W2912787197 hasAuthorship W2912787197A5005608086 @default.
• W2912787197 hasAuthorship W2912787197A5012386440 @default.
• W2912787197 hasAuthorship W2912787197A5024098116 @default.
• W2912787197 hasAuthorship W2912787197A5048901530 @default.
• W2912787197 hasAuthorship W2912787197A5052991414 @default.
• W2912787197 hasAuthorship W2912787197A5057723638 @default.
• W2912787197 hasBestOaLocation W29127871971 @default.
• W2912787197 hasConcept C109316439 @default.
• W2912787197 hasConcept C123012128 @default.
• W2912787197 hasConcept C134018914 @default.
• W2912787197 hasConcept C185592680 @default.
• W2912787197 hasConcept C195475562 @default.
• W2912787197 hasConcept C202751555 @default.
• W2912787197 hasConcept C2777411675 @default.
• W2912787197 hasConcept C2780972559 @default.
• W2912787197 hasConcept C55493867 @default.
• W2912787197 hasConcept C86803240 @default.
• W2912787197 hasConcept C98274493 @default.
• W2912787197 hasConceptScore W2912787197C109316439 @default.
• W2912787197 hasConceptScore W2912787197C123012128 @default.
• W2912787197 hasConceptScore W2912787197C134018914 @default.
• W2912787197 hasConceptScore W2912787197C185592680 @default.
• W2912787197 hasConceptScore W2912787197C195475562 @default.
• W2912787197 hasConceptScore W2912787197C202751555 @default.
• W2912787197 hasConceptScore W2912787197C2777411675 @default.
• W2912787197 hasConceptScore W2912787197C2780972559 @default.
• W2912787197 hasConceptScore W2912787197C55493867 @default.
• W2912787197 hasConceptScore W2912787197C86803240 @default.
• W2912787197 hasConceptScore W2912787197C98274493 @default.
• W2912787197 hasFunder F4320321873 @default.
• W2912787197 hasLocation W29127871971 @default.
• W2912787197 hasLocation W29127871972 @default.
• W2912787197 hasLocation W29127871973 @default.
• W2912787197 hasLocation W29127871974 @default.
• W2912787197 hasLocation W29127871975 @default.
• W2912787197 hasOpenAccess W2912787197 @default.
• W2912787197 hasPrimaryLocation W29127871971 @default.
• W2912787197 hasRelatedWork W151770906 @default.
• W2912787197 hasRelatedWork W2001295759 @default.
• W2912787197 hasRelatedWork W2009991541 @default.
• W2912787197 hasRelatedWork W2036530348 @default.
• W2912787197 hasRelatedWork W2045505273 @default.
• W2912787197 hasRelatedWork W2384753871 @default.
• W2912787197 hasRelatedWork W2387407221 @default.
• W2912787197 hasRelatedWork W2416964709 @default.
• W2912787197 hasRelatedWork W2990659495 @default.
• W2912787197 hasRelatedWork W3206717165 @default.
• W2912787197 hasVolume "2019" @default.

• next