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• W2912789514 abstract "Nipple-sparing mastectomy (NSM) is considered an oncologically sound procedure but necrosis of the nipple-areola complex (NAC) or skin flaps is a concern, particularly in the presence of risk factors. To increase the indications for NSM and decrease such complications, different procedures of surgical delay (SD) have been described.A retrospective analysis of patients who underwent SD for NSM at four Italian Breast Centers from 2014 to 2017 was performed. SD generally consisted of a periareolar or hemi-batwing incision, dissecting the skin and the NAC from the underlying breast tissue. NSM was scheduled after 2-3 weeks.Eighty-eight procedures were analyzed. Mild complications of SD were registered in 7.9% of cases. NSM was performed in 85 cases, whereas in three cases (3.4%) a skin-sparing mastectomy was necessary due to positivity of the retroareolar biopsy for cancer at SD. A direct-to- implant (DTI) reconstruction was performed in 42 cases (49.4%), while in 43 (50.6%) a tissue-expander (TE) was inserted. After NSM, eight complications (9.4%) were recorded: one total necrosis (1.2%), one partial necrosis (1.2%) and four minimal ischemia (4.7%) of NAC, one skin flap necrosis (1.2%), one haematoma (1.2%). In only two cases (2.3%) prosthesis removal was needed. Aesthetic outcome was evaluated excellent or good in 92.9% of cases. At a median follow-up of 24 months no local recurrences were seen.This is the largest series of SD with NSM presented so far in the literature. In our experience, SD extends indications for NSM in high-risk women." @default.
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• W2912789514 date "2019-08-01" @default.
• W2912789514 modified "2023-09-24" @default.
• W2912789514 title "Surgical delay may extend the indications for nipple-sparing mastectomy: A multicentric study" @default.
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• W2912789514 doi "https://doi.org/10.1016/j.ejso.2019.02.014" @default.
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