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- W2912790147 abstract "A case is reported of a 29-year-old woman with systemic lupus erythematosus (SLE) who developed clinical manifestations of pulmonary hypertension at a time when other manifestations of SLE were quiescent. She had a restrictive ventilatory defect but clear lung fields on chest x ray. Cardiac catheterization revealed severe pulmonary hypertension. Calculated pulmonary vascular resistance fell slightly after administration of oxygen and during infusion of vasodilators. Symptomatic improvement and a modest increase in right ventricular ejection fraction, as measured by radionuclide ventriculography, were noted following 1 week of oral hydralazine therapy. Clinically significant pulmonary hypertension is a rare complication of SLE and the increased pulmonary vascular resistance may not be entirely fixed. Cardiac catheterization and radionuclide ventriculography may be useful in assessing response to medical therapy." @default.
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- W2912790147 date "1980-10-01" @default.
- W2912790147 modified "2023-09-26" @default.
- W2912790147 title "Pulmonary hypertension in systemic lupus erythematosus: hemodynamics and effects of vasodilator therapy" @default.
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- W2912790147 doi "https://doi.org/10.1002/clc.4960030508" @default.
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