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- W2912795811 abstract "The KCL013 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (42 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro assays." @default.
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- W2912795811 date "2016-03-01" @default.
- W2912795811 modified "2023-10-17" @default.
- W2912795811 title "Generation of KCL013 research grade human embryonic stem cell line carrying a mutation in the HTT gene" @default.
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- W2912795811 doi "https://doi.org/10.1016/j.scr.2016.01.011" @default.
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