FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912796559> ?p ?o ?g. }

• W2912796559 abstract "Abstract Microbial cells need to adapt to changing environmental conditions to survive. There is an evolutionary advantage to grow fast; this requires high metabolic rates, and an efficient allocation of enzymatic resources. Here we study a general control theory called q ORAC, developed previously, which allows cells to adaptively control their enzyme allocations to achieve maximal steady state flux. The control is robust to perturbations in the environment, but those perturbations themselves do not feature in the control. In this paper we focus on the archetypical pathway, the linear chain with reversible Michaelis-Menten kinetics, together with q ORAC control. First we assume that the metabolic pathway is in quasi-steady state with respect to enzyme synthesis. Then we show that the map between steady state metabolite and enzyme concentrations is a smooth bijection. Using this information, we finally show that the unique (and hence flux-maximising) steady state of this system is locally stable. We provide further evidence that it may in fact be globally stable." @default.
• W2912796559 created "2019-02-21" @default.
• W2912796559 creator A5004505914 @default.
• W2912796559 creator A5022698323 @default.
• W2912796559 creator A5033178803 @default.
• W2912796559 date "2019-02-15" @default.
• W2912796559 modified "2023-10-03" @default.
• W2912796559 title "Stability of an adaptively controlled pathway maximising specific flux under varying conditions" @default.
• W2912796559 cites W1492559113 @default.
• W2912796559 cites W1985039493 @default.
• W2912796559 cites W2010060766 @default.
• W2912796559 cites W2010824267 @default.
• W2912796559 cites W2027257502 @default.
• W2912796559 cites W2039230661 @default.
• W2912796559 cites W2044463066 @default.
• W2912796559 cites W2046760236 @default.
• W2912796559 cites W2048243530 @default.
• W2912796559 cites W2058713700 @default.
• W2912796559 cites W2061659241 @default.
• W2912796559 cites W2068872007 @default.
• W2912796559 cites W2091793452 @default.
• W2912796559 cites W2111354165 @default.
• W2912796559 cites W2117597548 @default.
• W2912796559 cites W2131178894 @default.
• W2912796559 cites W2167900930 @default.
• W2912796559 cites W2416065856 @default.
• W2912796559 cites W2508698766 @default.
• W2912796559 cites W2951001909 @default.
• W2912796559 cites W4250523863 @default.
• W2912796559 doi "https://doi.org/10.1101/550343" @default.
• W2912796559 hasPublicationYear "2019" @default.
• W2912796559 type Work @default.
• W2912796559 sameAs 2912796559 @default.
• W2912796559 citedByCount "0" @default.
• W2912796559 crossrefType "posted-content" @default.
• W2912796559 hasAuthorship W2912796559A5004505914 @default.
• W2912796559 hasAuthorship W2912796559A5022698323 @default.
• W2912796559 hasAuthorship W2912796559A5033178803 @default.
• W2912796559 hasBestOaLocation W29127965591 @default.
• W2912796559 hasConcept C112972136 @default.
• W2912796559 hasConcept C11413529 @default.
• W2912796559 hasConcept C114614502 @default.
• W2912796559 hasConcept C119857082 @default.
• W2912796559 hasConcept C121332964 @default.
• W2912796559 hasConcept C134018914 @default.
• W2912796559 hasConcept C147789679 @default.
• W2912796559 hasConcept C148898269 @default.
• W2912796559 hasConcept C154945302 @default.
• W2912796559 hasConcept C178790620 @default.
• W2912796559 hasConcept C181199279 @default.
• W2912796559 hasConcept C185592680 @default.
• W2912796559 hasConcept C186060115 @default.
• W2912796559 hasConcept C192989942 @default.
• W2912796559 hasConcept C24424167 @default.
• W2912796559 hasConcept C2775924081 @default.
• W2912796559 hasConcept C2777477808 @default.
• W2912796559 hasConcept C2779306644 @default.
• W2912796559 hasConcept C33923547 @default.
• W2912796559 hasConcept C41008148 @default.
• W2912796559 hasConcept C41183919 @default.
• W2912796559 hasConcept C47446073 @default.
• W2912796559 hasConcept C48103436 @default.
• W2912796559 hasConcept C55493867 @default.
• W2912796559 hasConcept C56856141 @default.
• W2912796559 hasConcept C62520636 @default.
• W2912796559 hasConcept C68709404 @default.
• W2912796559 hasConcept C70818257 @default.
• W2912796559 hasConcept C8171440 @default.
• W2912796559 hasConcept C86803240 @default.
• W2912796559 hasConceptScore W2912796559C112972136 @default.
• W2912796559 hasConceptScore W2912796559C11413529 @default.
• W2912796559 hasConceptScore W2912796559C114614502 @default.
• W2912796559 hasConceptScore W2912796559C119857082 @default.
• W2912796559 hasConceptScore W2912796559C121332964 @default.
• W2912796559 hasConceptScore W2912796559C134018914 @default.
• W2912796559 hasConceptScore W2912796559C147789679 @default.
• W2912796559 hasConceptScore W2912796559C148898269 @default.
• W2912796559 hasConceptScore W2912796559C154945302 @default.
• W2912796559 hasConceptScore W2912796559C178790620 @default.
• W2912796559 hasConceptScore W2912796559C181199279 @default.
• W2912796559 hasConceptScore W2912796559C185592680 @default.
• W2912796559 hasConceptScore W2912796559C186060115 @default.
• W2912796559 hasConceptScore W2912796559C192989942 @default.
• W2912796559 hasConceptScore W2912796559C24424167 @default.
• W2912796559 hasConceptScore W2912796559C2775924081 @default.
• W2912796559 hasConceptScore W2912796559C2777477808 @default.
• W2912796559 hasConceptScore W2912796559C2779306644 @default.
• W2912796559 hasConceptScore W2912796559C33923547 @default.
• W2912796559 hasConceptScore W2912796559C41008148 @default.
• W2912796559 hasConceptScore W2912796559C41183919 @default.
• W2912796559 hasConceptScore W2912796559C47446073 @default.
• W2912796559 hasConceptScore W2912796559C48103436 @default.
• W2912796559 hasConceptScore W2912796559C55493867 @default.
• W2912796559 hasConceptScore W2912796559C56856141 @default.
• W2912796559 hasConceptScore W2912796559C62520636 @default.
• W2912796559 hasConceptScore W2912796559C68709404 @default.
• W2912796559 hasConceptScore W2912796559C70818257 @default.
• W2912796559 hasConceptScore W2912796559C8171440 @default.
• W2912796559 hasConceptScore W2912796559C86803240 @default.
• W2912796559 hasLocation W29127965591 @default.

• next