Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912800416> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2912800416 endingPage "77" @default.
- W2912800416 startingPage "73" @default.
- W2912800416 abstract "Thiamine diphosphate (ThDP) is an essential cofactor for important enzymes in carbohydrate, amino acid and lipid metabolisms. It is also known that thiamine plays an important role in stress response of some organisms. In this study, we focused on the effect of thiamine on stress responses triggered by various stress agents. For this purpose, firstly, viability of Schizosaccharomyces pombe cell cultures was examined under oxidative, osmotic and heat stresses. The highest tolerance observed in cell viability due to the presence of extracellular thiamine (1.5 µM) was found only against oxidative stress. Then, enzyme activity of catalase and superoxide dismutase (SOD) involved in antioxidant defense mechanism and the expression analysis of genes encoding enzymes related to glucose metabolism and stress response pathways were investigated under oxidative stress. In this condition, it was not observed any difference in SOD and catalase activities, and their gene expressions due to the presence of thiamine, whereas the upregulation of pyruvate dehydrogenase (pdb1), transketolase (SPBC2G5.05), fructose-1,6-bis-phosphatase (fbp1) and the downregulation of pyruvate decarboxylase (pdc201) were observed. In conclusion, these findings suggest that extracellular thiamine leading to oxidative stress resistance have an impact on the regulation of glucose metabolism by shifting the energy generation from fermentation to respiration." @default.
- W2912800416 created "2019-02-21" @default.
- W2912800416 creator A5003285078 @default.
- W2912800416 creator A5067365528 @default.
- W2912800416 date "2019-01-31" @default.
- W2912800416 modified "2023-10-03" @default.
- W2912800416 title "Thiamine leads to oxidative stress resistance via regulation of the glucose metabolism" @default.
- W2912800416 cites W1500937540 @default.
- W2912800416 cites W1590010999 @default.
- W2912800416 cites W17646219 @default.
- W2912800416 cites W1910125601 @default.
- W2912800416 cites W1973824858 @default.
- W2912800416 cites W1986580287 @default.
- W2912800416 cites W1989229525 @default.
- W2912800416 cites W1995754833 @default.
- W2912800416 cites W2014129177 @default.
- W2912800416 cites W2020585948 @default.
- W2912800416 cites W2022760174 @default.
- W2912800416 cites W2037059734 @default.
- W2912800416 cites W2051133106 @default.
- W2912800416 cites W2057451998 @default.
- W2912800416 cites W2060793607 @default.
- W2912800416 cites W2069124186 @default.
- W2912800416 cites W2079121387 @default.
- W2912800416 cites W2085593205 @default.
- W2912800416 cites W2087661216 @default.
- W2912800416 cites W2108244474 @default.
- W2912800416 cites W2123155459 @default.
- W2912800416 cites W2134809769 @default.
- W2912800416 cites W2149856015 @default.
- W2912800416 cites W2160877304 @default.
- W2912800416 cites W240221521 @default.
- W2912800416 cites W2528251580 @default.
- W2912800416 cites W2765121118 @default.
- W2912800416 cites W2898502055 @default.
- W2912800416 cites W2007396424 @default.
- W2912800416 doi "https://doi.org/10.14715/cmb/2019.65.1.13" @default.
- W2912800416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30782298" @default.
- W2912800416 hasPublicationYear "2019" @default.
- W2912800416 type Work @default.
- W2912800416 sameAs 2912800416 @default.
- W2912800416 citedByCount "10" @default.
- W2912800416 countsByYear W29128004162020 @default.
- W2912800416 countsByYear W29128004162021 @default.
- W2912800416 countsByYear W29128004162022 @default.
- W2912800416 countsByYear W29128004162023 @default.
- W2912800416 crossrefType "journal-article" @default.
- W2912800416 hasAuthorship W2912800416A5003285078 @default.
- W2912800416 hasAuthorship W2912800416A5067365528 @default.
- W2912800416 hasBestOaLocation W29128004161 @default.
- W2912800416 hasConcept C103432212 @default.
- W2912800416 hasConcept C17093226 @default.
- W2912800416 hasConcept C181199279 @default.
- W2912800416 hasConcept C185592680 @default.
- W2912800416 hasConcept C2775838275 @default.
- W2912800416 hasConcept C2776151105 @default.
- W2912800416 hasConcept C2776203871 @default.
- W2912800416 hasConcept C2777344606 @default.
- W2912800416 hasConcept C2778979269 @default.
- W2912800416 hasConcept C2781281423 @default.
- W2912800416 hasConcept C55493867 @default.
- W2912800416 hasConcept C86803240 @default.
- W2912800416 hasConcept C88099638 @default.
- W2912800416 hasConceptScore W2912800416C103432212 @default.
- W2912800416 hasConceptScore W2912800416C17093226 @default.
- W2912800416 hasConceptScore W2912800416C181199279 @default.
- W2912800416 hasConceptScore W2912800416C185592680 @default.
- W2912800416 hasConceptScore W2912800416C2775838275 @default.
- W2912800416 hasConceptScore W2912800416C2776151105 @default.
- W2912800416 hasConceptScore W2912800416C2776203871 @default.
- W2912800416 hasConceptScore W2912800416C2777344606 @default.
- W2912800416 hasConceptScore W2912800416C2778979269 @default.
- W2912800416 hasConceptScore W2912800416C2781281423 @default.
- W2912800416 hasConceptScore W2912800416C55493867 @default.
- W2912800416 hasConceptScore W2912800416C86803240 @default.
- W2912800416 hasConceptScore W2912800416C88099638 @default.
- W2912800416 hasIssue "1" @default.
- W2912800416 hasLocation W29128004161 @default.
- W2912800416 hasLocation W29128004162 @default.
- W2912800416 hasOpenAccess W2912800416 @default.
- W2912800416 hasPrimaryLocation W29128004161 @default.
- W2912800416 hasRelatedWork W1914069668 @default.
- W2912800416 hasRelatedWork W1976408867 @default.
- W2912800416 hasRelatedWork W1981159588 @default.
- W2912800416 hasRelatedWork W2025875085 @default.
- W2912800416 hasRelatedWork W2082729015 @default.
- W2912800416 hasRelatedWork W2093285136 @default.
- W2912800416 hasRelatedWork W2117849723 @default.
- W2912800416 hasRelatedWork W2208020336 @default.
- W2912800416 hasRelatedWork W2966747629 @default.
- W2912800416 hasRelatedWork W2993730345 @default.
- W2912800416 hasVolume "65" @default.
- W2912800416 isParatext "false" @default.
- W2912800416 isRetracted "false" @default.
- W2912800416 magId "2912800416" @default.
- W2912800416 workType "article" @default.