Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912801710> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2912801710 endingPage "S1567" @default.
- W2912801710 startingPage "S1566" @default.
- W2912801710 abstract "Elevated liver function tests (LFTs) can be caused by numerous etiologies such as infection, choledocholithiasis, toxins, and chronic disorders. It can also occur after invasive procedures like endoscopic retrograde cholangiopancreatography (ERCP). Here we present the case of a young woman who suffered an unusual complication, prolonged jaundice after ERCP, of which the etiology was initially unclear. A 32-year-old woman with history of cholelithiasis presented with abdominal pain. Her LFTs were elevated, including total bilirubin of 3.8 and direct bilirubin of 2.1. A right upper quadrant ultrasound revealed cholelithiasis and common bile duct (CBD) dilation at 11 mm. ERCP confirmed these findings as well as a distal CBD stone which was removed; a plastic biliary stent was placed. Gastritis was noted and confirmed histologically to be due to H. pylori. She was discharged on pantoprazole, clarithromycin, and amoxicillin. As an outpatient, she underwent laparoscopic cholecystectomy; at this time her total bilirubin was 3.4. At follow-up two weeks later, she complained of continued pruritis and jaundice. She was admitted as her total bilirubin was found to be worsening at 4.1. A second ERCP did not reveal bile leak, stenosis, or stone retention. She was discharged however at one week follow-up she still reported pruritis and jaundice. Extensive laboratory work-up including viral and autoimmune hepatitis were negative. On careful review, it was found that she had been erroneously prescribed four weeks of clarithromycin, instead of the standard two week regimen for H. pylori. The drug was discontinued. At follow-up four weeks later, her pruritis and jaundice had resolved and her LFTs were greatly improved (total bilirubin 1.1). Six months later all liver enzymes were within normal range. In this case, the cause of the patient's jaundice and elevated LFTs was initially unclear. Prolonged jaundice after ERCP and subsequent cholecystectomy is a rare complication. Post-cholecystectomy jaundice could be caused by ischemia, viral hepatitis, bile leak, biliary stricture, or infection. Here, a second ERCP did not reveal any such complications which could have explained her symptoms. The chronology of events and LFT trends favored the cause of liver insult as due to clarithromycin. We posited that this was due to drug-induced liver injury (DILI). Discontinuation of the offending agent, as in our patient, lead to resolution of symptoms and laboratory derangements.FigureFigureFigure" @default.
- W2912801710 created "2019-02-21" @default.
- W2912801710 creator A5007891396 @default.
- W2912801710 creator A5067139481 @default.
- W2912801710 creator A5086378572 @default.
- W2912801710 date "2017-10-01" @default.
- W2912801710 modified "2023-10-18" @default.
- W2912801710 title "An Unusual Cause of Prolonged Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Jaundice" @default.
- W2912801710 doi "https://doi.org/10.14309/00000434-201710001-02935" @default.
- W2912801710 hasPublicationYear "2017" @default.
- W2912801710 type Work @default.
- W2912801710 sameAs 2912801710 @default.
- W2912801710 citedByCount "1" @default.
- W2912801710 countsByYear W29128017102018 @default.
- W2912801710 crossrefType "journal-article" @default.
- W2912801710 hasAuthorship W2912801710A5007891396 @default.
- W2912801710 hasAuthorship W2912801710A5067139481 @default.
- W2912801710 hasAuthorship W2912801710A5086378572 @default.
- W2912801710 hasConcept C126322002 @default.
- W2912801710 hasConcept C141071460 @default.
- W2912801710 hasConcept C2775967933 @default.
- W2912801710 hasConcept C2776641081 @default.
- W2912801710 hasConcept C2776884468 @default.
- W2912801710 hasConcept C2778444009 @default.
- W2912801710 hasConcept C2778456037 @default.
- W2912801710 hasConcept C2778593092 @default.
- W2912801710 hasConcept C71924100 @default.
- W2912801710 hasConcept C90924648 @default.
- W2912801710 hasConceptScore W2912801710C126322002 @default.
- W2912801710 hasConceptScore W2912801710C141071460 @default.
- W2912801710 hasConceptScore W2912801710C2775967933 @default.
- W2912801710 hasConceptScore W2912801710C2776641081 @default.
- W2912801710 hasConceptScore W2912801710C2776884468 @default.
- W2912801710 hasConceptScore W2912801710C2778444009 @default.
- W2912801710 hasConceptScore W2912801710C2778456037 @default.
- W2912801710 hasConceptScore W2912801710C2778593092 @default.
- W2912801710 hasConceptScore W2912801710C71924100 @default.
- W2912801710 hasConceptScore W2912801710C90924648 @default.
- W2912801710 hasLocation W29128017101 @default.
- W2912801710 hasOpenAccess W2912801710 @default.
- W2912801710 hasPrimaryLocation W29128017101 @default.
- W2912801710 hasRelatedWork W2002689947 @default.
- W2912801710 hasRelatedWork W2016536068 @default.
- W2912801710 hasRelatedWork W2060384727 @default.
- W2912801710 hasRelatedWork W2135440264 @default.
- W2912801710 hasRelatedWork W2234528805 @default.
- W2912801710 hasRelatedWork W2267022974 @default.
- W2912801710 hasRelatedWork W2324303267 @default.
- W2912801710 hasRelatedWork W2562938923 @default.
- W2912801710 hasRelatedWork W2796180366 @default.
- W2912801710 hasRelatedWork W3045732343 @default.
- W2912801710 hasVolume "112" @default.
- W2912801710 isParatext "false" @default.
- W2912801710 isRetracted "false" @default.
- W2912801710 magId "2912801710" @default.
- W2912801710 workType "article" @default.