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• W2912808614 startingPage "152" @default.
• W2912808614 abstract "Advanced prostate cancer (PCa) is a prominent cause of cancer death in men; positron emission tomography (PET) imaging may play a relevant role in detecting metastases and thus allowing a more tailored therapy in these patients. Radioligand therapy (RLT) may also gain relevance as a treatment strategy in advanced disease. The aim of this review is to highlight how the recently developed theranostic processes may become a part of both the available diagnostic and the therapy arsenal in advanced PCa patients. An expert panel of nuclear medicine physicians and a urologist, highly experienced in the fields of radionuclide imaging and RLT in advanced PCa, performed a nonsystematic review of the current indications, performance, limitations, and potential future developments of the currently available options in PCa theranostics. Among PET radiotracers, prostate-specific membrane antigen (PSMA)-based compounds in advanced PCa are the focus of a continuously growing interest, mostly due to their potential relevance as theranostic agents. The impact of PSMA-based PET/computed tomography imaging on treatment strategies and prognosis is promising, but still not unquestionably clear. Potential applications may include a role as a gatekeeper to PSMA-directed RLT, as well as monitoring the spread of systemic disease. Currently, initial results seem to substantiate the role of PSMA-directed RLT in terms of feasibility and efficacy. PSMA is a promising molecule for both imaging and therapy in advanced PCa patients; nevertheless, further studies are needed to investigate its role and to determine the impact of its side effects and its overall strategy outcome. Prostate-specific membrane antigen (PSMA), a protein, is highly expressed on prostate cancer cells. The possibility to perform diagnostic imaging and subsequently administer therapies by the means of the same molecule is called “theranostics”. In patients with advanced prostate cancer, PSMA might have a role in detecting disease spread through both positron emission tomography and single-photon emission computed tomography imaging, while treating prostate cancer systemic localizations with radioligand therapy. Further studies are needed to better determine patients’ risks and benefits of these therapeutic approaches." @default.
• W2912808614 created "2019-02-21" @default.
• W2912808614 creator A5006830341 @default.
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• W2912808614 creator A5086087400 @default.
• W2912808614 date "2019-03-01" @default.
• W2912808614 modified "2023-10-17" @default.
• W2912808614 title "Theranostics for Advanced Prostate Cancer: Current Indications and Future Developments" @default.
• W2912808614 cites W1232915009 @default.
• W2912808614 cites W1490266165 @default.
• W2912808614 cites W1788773500 @default.
• W2912808614 cites W1900676315 @default.
• W2912808614 cites W1965617754 @default.
• W2912808614 cites W1973942000 @default.
• W2912808614 cites W1984585246 @default.
• W2912808614 cites W1998345392 @default.
• W2912808614 cites W1998403654 @default.
• W2912808614 cites W2013797019 @default.
• W2912808614 cites W2014999922 @default.
• W2912808614 cites W2020409101 @default.
• W2912808614 cites W2030940240 @default.
• W2912808614 cites W2033261019 @default.
• W2912808614 cites W2033819744 @default.
• W2912808614 cites W2038578630 @default.
• W2912808614 cites W2050551827 @default.
• W2912808614 cites W2066588899 @default.
• W2912808614 cites W2071633854 @default.
• W2912808614 cites W2075601928 @default.
• W2912808614 cites W2079474262 @default.
• W2912808614 cites W2080006760 @default.
• W2912808614 cites W2080439368 @default.
• W2912808614 cites W2092776013 @default.
• W2912808614 cites W2100550345 @default.
• W2912808614 cites W2103959341 @default.
• W2912808614 cites W2110534364 @default.
• W2912808614 cites W2113746964 @default.
• W2912808614 cites W2115158465 @default.
• W2912808614 cites W2120292596 @default.
• W2912808614 cites W2120873855 @default.
• W2912808614 cites W2123526148 @default.
• W2912808614 cites W2125363072 @default.
• W2912808614 cites W2126812800 @default.
• W2912808614 cites W2129260701 @default.
• W2912808614 cites W2134019417 @default.
• W2912808614 cites W2134364976 @default.
• W2912808614 cites W2137467802 @default.
• W2912808614 cites W2137571973 @default.
• W2912808614 cites W2137670219 @default.
• W2912808614 cites W2141454098 @default.
• W2912808614 cites W2147136637 @default.
• W2912808614 cites W2166918329 @default.
• W2912808614 cites W2167077736 @default.
• W2912808614 cites W2170794639 @default.
• W2912808614 cites W2175765437 @default.
• W2912808614 cites W2177809753 @default.
• W2912808614 cites W2234163738 @default.
• W2912808614 cites W2252550361 @default.
• W2912808614 cites W2264333554 @default.
• W2912808614 cites W2278392405 @default.
• W2912808614 cites W2281201358 @default.
• W2912808614 cites W2301515918 @default.
• W2912808614 cites W2302508993 @default.
• W2912808614 cites W2303817381 @default.
• W2912808614 cites W2304896218 @default.
• W2912808614 cites W2312576106 @default.
• W2912808614 cites W2315998085 @default.
• W2912808614 cites W2346537962 @default.
• W2912808614 cites W2395284164 @default.
• W2912808614 cites W2397136240 @default.
• W2912808614 cites W2410782911 @default.
• W2912808614 cites W2414412661 @default.
• W2912808614 cites W2416073795 @default.
• W2912808614 cites W2467018059 @default.
• W2912808614 cites W2470255787 @default.
• W2912808614 cites W2511755939 @default.
• W2912808614 cites W2518199070 @default.
• W2912808614 cites W2520024435 @default.
• W2912808614 cites W2523333323 @default.
• W2912808614 cites W2532226140 @default.
• W2912808614 cites W2541665535 @default.
• W2912808614 cites W2558086743 @default.
• W2912808614 cites W2572709133 @default.
• W2912808614 cites W2593925322 @default.
• W2912808614 cites W2599305587 @default.
• W2912808614 cites W2605392160 @default.
• W2912808614 cites W2606187374 @default.
• W2912808614 cites W2609771428 @default.
• W2912808614 cites W2610724978 @default.
• W2912808614 cites W2612027160 @default.
• W2912808614 cites W2614800517 @default.
• W2912808614 cites W2619811894 @default.
• W2912808614 cites W2625296464 @default.
• W2912808614 cites W2762824224 @default.

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