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- W2912823021 abstract "Abstract An efficient microwave‐assisted one‐pot method has been developed for the construction of pyrrolidine fused bis‐spirooxindoles through insitu generated azomethine ylide from decarboxylative condensation of isatins and primary α‐amino acids with concomitant [3+2] cycloaddition of 3‐alkenyl oxindoles. These reactions were effectively accelerated by microwave irradiation in ethanol solvent without any additives or catalyst and enable broad substrate scope, atom‐economy, eco‐friendly, and good yields. The structure and stereochemistry of pyrrolidine fused bis‐spirooxindole ring was unambiguously established by single‐crystal X‐ray analysis." @default.
- W2912823021 created "2019-02-21" @default.
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- W2912823021 date "2019-02-05" @default.
- W2912823021 modified "2023-09-30" @default.
- W2912823021 title "Microwave‐Assisted One‐Pot [3+2] Cycloaddition of Azomethine Ylides and 3‐Alkenyl Oxindoles: A Facile Approach to Pyrrolidine‐Fused Bis‐Spirooxindoles" @default.
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- W2912823021 doi "https://doi.org/10.1002/slct.201802847" @default.
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