FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912839474> ?p ?o ?g. }

• W2912839474 endingPage "16399" @default.
• W2912839474 startingPage "16389" @default.
• W2912839474 abstract "Abstract We studied the effects of electrical stimulation on insulin release from rat insulinoma (INS‐1) cells. The anodal/cathodal biphasic stimulation (ACBPS) electrical waveform resulted in a voltage‐ and stimulation duration‐dependent increase in insulin release. ACBPS elicited insulin release both in the presence and absence of glucose. Basal and ACBPS‐induced insulin secretion could be inhibited by mitochondrial poisons and calcium channel blockers, indicating that insulin release was dependent on adenosine triphosphate (ATP) and the influx of calcium. ACBPS parameters that released insulin caused no detectable plasma membrane damage or cytotoxicity, although temporary morphological changes could be observed immediately after ACBPS. ACBPS did not alter the plasma membrane transmembrane potential but did cause pronounced uptake of MitoTracker Red into the mitochondrial membrane, indicating an increased mitochondrial membrane potential. While the ATP:ADP ratio after ACBPS did not change, the guanosine triphosphate (GTP) levels increased and increased GTP levels have previously been associated with insulin release in INS‐1 cells. These results provide evidence that ACBPS can have significant biological effects on cells. In the case of INS‐1 cells, ACBPS promotes insulin release without causing cytotoxicity." @default.
• W2912839474 created "2019-02-21" @default.
• W2912839474 creator A5002727698 @default.
• W2912839474 creator A5009225650 @default.
• W2912839474 creator A5024622700 @default.
• W2912839474 creator A5029136277 @default.
• W2912839474 creator A5039144282 @default.
• W2912839474 creator A5046170141 @default.
• W2912839474 date "2019-02-11" @default.
• W2912839474 modified "2023-09-26" @default.
• W2912839474 title "The effect of anodal/cathodal biphasic electrical stimulation on insulin release" @default.
• W2912839474 cites W1434984406 @default.
• W2912839474 cites W1775749144 @default.
• W2912839474 cites W1965392584 @default.
• W2912839474 cites W1988568489 @default.
• W2912839474 cites W1992050864 @default.
• W2912839474 cites W2009269237 @default.
• W2912839474 cites W2014058353 @default.
• W2912839474 cites W2026444172 @default.
• W2912839474 cites W2028431915 @default.
• W2912839474 cites W2029120648 @default.
• W2912839474 cites W2041166828 @default.
• W2912839474 cites W2042102929 @default.
• W2912839474 cites W2051061588 @default.
• W2912839474 cites W2053697597 @default.
• W2912839474 cites W2055480009 @default.
• W2912839474 cites W2072984035 @default.
• W2912839474 cites W2093709619 @default.
• W2912839474 cites W2144761555 @default.
• W2912839474 cites W2153134360 @default.
• W2912839474 cites W2170002187 @default.
• W2912839474 cites W2331996676 @default.
• W2912839474 cites W2340964313 @default.
• W2912839474 cites W2518938775 @default.
• W2912839474 cites W2521960911 @default.
• W2912839474 cites W2555115997 @default.
• W2912839474 cites W2763881952 @default.
• W2912839474 cites W2806801121 @default.
• W2912839474 cites W2887477420 @default.
• W2912839474 cites W4243903519 @default.
• W2912839474 cites W52690082 @default.
• W2912839474 doi "https://doi.org/10.1002/jcp.28307" @default.
• W2912839474 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30746686" @default.
• W2912839474 hasPublicationYear "2019" @default.
• W2912839474 type Work @default.
• W2912839474 sameAs 2912839474 @default.
• W2912839474 citedByCount "2" @default.
• W2912839474 countsByYear W29128394742019 @default.
• W2912839474 countsByYear W29128394742022 @default.
• W2912839474 crossrefType "journal-article" @default.
• W2912839474 hasAuthorship W2912839474A5002727698 @default.
• W2912839474 hasAuthorship W2912839474A5009225650 @default.
• W2912839474 hasAuthorship W2912839474A5024622700 @default.
• W2912839474 hasAuthorship W2912839474A5029136277 @default.
• W2912839474 hasAuthorship W2912839474A5039144282 @default.
• W2912839474 hasAuthorship W2912839474A5046170141 @default.
• W2912839474 hasConcept C118716 @default.
• W2912839474 hasConcept C126322002 @default.
• W2912839474 hasConcept C134018914 @default.
• W2912839474 hasConcept C181199279 @default.
• W2912839474 hasConcept C181911157 @default.
• W2912839474 hasConcept C185592680 @default.
• W2912839474 hasConcept C24998067 @default.
• W2912839474 hasConcept C2777995097 @default.
• W2912839474 hasConcept C2779306644 @default.
• W2912839474 hasConcept C2779564974 @default.
• W2912839474 hasConcept C519063684 @default.
• W2912839474 hasConcept C55493867 @default.
• W2912839474 hasConcept C71924100 @default.
• W2912839474 hasConcept C86803240 @default.
• W2912839474 hasConceptScore W2912839474C118716 @default.
• W2912839474 hasConceptScore W2912839474C126322002 @default.
• W2912839474 hasConceptScore W2912839474C134018914 @default.
• W2912839474 hasConceptScore W2912839474C181199279 @default.
• W2912839474 hasConceptScore W2912839474C181911157 @default.
• W2912839474 hasConceptScore W2912839474C185592680 @default.
• W2912839474 hasConceptScore W2912839474C24998067 @default.
• W2912839474 hasConceptScore W2912839474C2777995097 @default.
• W2912839474 hasConceptScore W2912839474C2779306644 @default.
• W2912839474 hasConceptScore W2912839474C2779564974 @default.
• W2912839474 hasConceptScore W2912839474C519063684 @default.
• W2912839474 hasConceptScore W2912839474C55493867 @default.
• W2912839474 hasConceptScore W2912839474C71924100 @default.
• W2912839474 hasConceptScore W2912839474C86803240 @default.
• W2912839474 hasIssue "9" @default.
• W2912839474 hasLocation W29128394741 @default.
• W2912839474 hasLocation W29128394742 @default.
• W2912839474 hasOpenAccess W2912839474 @default.
• W2912839474 hasPrimaryLocation W29128394741 @default.
• W2912839474 hasRelatedWork W1983641721 @default.
• W2912839474 hasRelatedWork W1995945960 @default.
• W2912839474 hasRelatedWork W2026226896 @default.
• W2912839474 hasRelatedWork W2032033851 @default.
• W2912839474 hasRelatedWork W2041678535 @default.
• W2912839474 hasRelatedWork W2066345847 @default.
• W2912839474 hasRelatedWork W2089387278 @default.
• W2912839474 hasRelatedWork W2095179743 @default.
• W2912839474 hasRelatedWork W2130904138 @default.

• next