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- W2912854911 abstract "Background: Percutaneous Transluminal Angioplasty (PTA) of the lower limb improves arterial flow and claudication symptoms, but the effects on cutaneous microvascular perfusion and reactivity have not been previously reported. Report: Cutaneous microvascular function in the feet was assessed in 12 patients with intermittent claudication before and after PTA using Laser Doppler Fluximetry (LDF) with transcutaneous iontophoretic administration of acetylcholine and sodium nitroprusside. Maximum vasodilator responses to both endothelial-dependent and independent vasodilators were increased following PTA. Conclusions: Large vessel intervention to improve macrovascular flow has additional benefits on the downstream cutaneous microcirculation to improve vasodilator responsiveness. These effects may be clinically important to reduce the risk of ischaemic ulceration and tissue breakdown. Effects of Lower Limb Angioplasty on Endothelial-Dependent and -Independent Microvascular ReactivityEJVES ExtraVol. 22Issue 5PreviewPercutaneous Transluminal Angioplasty (PTA) of the lower limb improves arterial flow and claudication symptoms, but the effects on cutaneous microvascular perfusion and reactivity have not been previously reported. Full-Text PDF Open Access" @default.
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- W2912854911 date "2011-12-01" @default.
- W2912854911 modified "2023-09-29" @default.
- W2912854911 title "Effects of Lower Limb Angioplasty on Endothelial-Dependent and -Independent Microvascular Reactivity" @default.
- W2912854911 doi "https://doi.org/10.1016/j.ejvs.2011.09.001" @default.
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