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- W2912861073 abstract "Background: Cancer stem cells (CSCs) are a rare population of tumor cells, which play an important role in tumor initiation, progression, and maintenance. The concept that cancer cells arise from stem cells was presented about 150 years ago. Recently, this hypothesis was renewed considering the heterogeneity of tumor cells. CSCs are resistant to chemo- and radio-therapy. Therefore, targeting CSCs could be a novel and effective strategy to struggle with tumor cells. Objective: In this mini-review, we highlight that different immunotherapeutic approaches can be used to target cancer cells and eradicate different tumor cells. The most important targets are specific markers recognized on the CSC surface as CSC antigens such as CD44, CD133, Aldehyde Dehydrogenase (ALDH), and SOX family members. This article emphasizes recent advances in CSCs in cancer therapy. Results: Our results present that CSC antigens play an important role in tumor initiation, especially in the cells that are resistant to chemo- and radiotherapy agents. Therefore, they are ideal targets for cancer immunotherapy, for instance, in developing different types of cancer vaccines or antibodies against tumor cells. Conclusion: The current studies related to cancer immunotherapy through targeting the CSC antigens based on their properties are briefly summarized. Altogether, CSC antigens can be efficiently targeted to treat cancer patients." @default.
- W2912861073 created "2019-02-21" @default.
- W2912861073 creator A5001462743 @default.
- W2912861073 creator A5054264371 @default.
- W2912861073 creator A5063711342 @default.
- W2912861073 creator A5088462152 @default.
- W2912861073 date "2019-04-16" @default.
- W2912861073 modified "2023-10-06" @default.
- W2912861073 title "A New Approach for Cancer Immunotherapy Based on the Cancer Stem Cell Antigens Properties" @default.
- W2912861073 cites W1552454396 @default.
- W2912861073 cites W1651067575 @default.
- W2912861073 cites W1789976271 @default.
- W2912861073 cites W1969600175 @default.
- W2912861073 cites W1970949498 @default.
- W2912861073 cites W1971424904 @default.
- W2912861073 cites W1971844380 @default.
- W2912861073 cites W1975881545 @default.
- W2912861073 cites W1977849423 @default.
- W2912861073 cites W1979421565 @default.
- W2912861073 cites W1982321597 @default.
- W2912861073 cites W1982544588 @default.
- W2912861073 cites W1984413324 @default.
- W2912861073 cites W1984658883 @default.
- W2912861073 cites W1986815130 @default.
- W2912861073 cites W1990757263 @default.
- W2912861073 cites W1992699637 @default.
- W2912861073 cites W1998181914 @default.
- W2912861073 cites W1999356404 @default.
- W2912861073 cites W2003554910 @default.
- W2912861073 cites W2007149178 @default.
- W2912861073 cites W2011090802 @default.
- W2912861073 cites W2018692299 @default.
- W2912861073 cites W2021404182 @default.
- W2912861073 cites W2022007751 @default.
- W2912861073 cites W2023171799 @default.
- W2912861073 cites W2023316892 @default.
- W2912861073 cites W2024520801 @default.
- W2912861073 cites W2026379260 @default.
- W2912861073 cites W2029231546 @default.
- W2912861073 cites W2033648590 @default.
- W2912861073 cites W2040102705 @default.
- W2912861073 cites W2040991839 @default.
- W2912861073 cites W2044360617 @default.
- W2912861073 cites W2045459656 @default.
- W2912861073 cites W2045882462 @default.
- W2912861073 cites W2050754173 @default.
- W2912861073 cites W2052750156 @default.
- W2912861073 cites W2054114326 @default.
- W2912861073 cites W2054183077 @default.
- W2912861073 cites W2060211329 @default.
- W2912861073 cites W2060551076 @default.
- W2912861073 cites W2062069005 @default.
- W2912861073 cites W2067415629 @default.
- W2912861073 cites W2070608192 @default.
- W2912861073 cites W2071123870 @default.
- W2912861073 cites W2072778582 @default.
- W2912861073 cites W2079777624 @default.
- W2912861073 cites W2082379910 @default.
- W2912861073 cites W2083157454 @default.
- W2912861073 cites W2083274861 @default.
- W2912861073 cites W2088635881 @default.
- W2912861073 cites W2089542415 @default.
- W2912861073 cites W2090982381 @default.
- W2912861073 cites W2091997954 @default.
- W2912861073 cites W2092807173 @default.
- W2912861073 cites W2094040645 @default.
- W2912861073 cites W2100723703 @default.
- W2912861073 cites W2102394111 @default.
- W2912861073 cites W2102616892 @default.
- W2912861073 cites W2103255385 @default.
- W2912861073 cites W2109678171 @default.
- W2912861073 cites W2114415068 @default.
- W2912861073 cites W2121362686 @default.
- W2912861073 cites W2122412604 @default.
- W2912861073 cites W2124255173 @default.
- W2912861073 cites W2125192790 @default.
- W2912861073 cites W2139334516 @default.
- W2912861073 cites W2140254135 @default.
- W2912861073 cites W2142935250 @default.
- W2912861073 cites W2143995836 @default.
- W2912861073 cites W2146601467 @default.
- W2912861073 cites W2153101406 @default.
- W2912861073 cites W2154207271 @default.
- W2912861073 cites W2156149964 @default.
- W2912861073 cites W2158362968 @default.
- W2912861073 cites W2159222883 @default.
- W2912861073 cites W2163879994 @default.
- W2912861073 cites W2165803132 @default.
- W2912861073 cites W2168414172 @default.
- W2912861073 cites W2169752217 @default.
- W2912861073 cites W2193999202 @default.
- W2912861073 cites W2497255755 @default.
- W2912861073 cites W2511078803 @default.
- W2912861073 cites W2782007611 @default.
- W2912861073 cites W2783523953 @default.
- W2912861073 cites W2784686711 @default.
- W2912861073 doi "https://doi.org/10.2174/1566524019666190204114721" @default.
- W2912861073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30714514" @default.
- W2912861073 hasPublicationYear "2019" @default.
- W2912861073 type Work @default.