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• W2912863036 abstract "Background Ambulation is an essential aspect of daily living and is often impaired after brain and spinal cord injuries. Despite the implementation of standard neurorehabilitative care, locomotor recovery is often incomplete. Objective In this randomized, sham-controlled, double-blind, parallel design study, we aimed to determine if anodal transcutaneous spinal direct current stimulation (anodal tsDCS) could improve training effects on locomotion compared to sham (sham tsDCS) in healthy subjects. Methods: 43 participants underwent a single backwards locomotion training (BLT) session on a reverse treadmill with concurrent anodal (n = 22) or sham (n = 21) tsDCS. The primary outcome measure was speed gain measured 24 h post-training. We hypothesized that anodal tsDCS + BLT would improve training effects on backward locomotor speed compared to sham tsDCS + BLT. A subset of participants (n = 31) returned for two additional training days of either anodal (n = 16) or sham (n = 15) tsDCS and underwent (n = 29) H-reflex testing immediately before, immediately after, and 30 min post-training over three consecutive days. Results A single session of anodal tsDCS + BLT elicited greater speed gain at 24 h relative to sham tsDCS + BLT (p = 0.008, two-sample t-test, adjusted for one interim analysis after the initial 12 subjects). Anodal tsDCS + BLT resulted in higher retention of the acquired skill at day 30 relative to sham tsDCS + BLT (p = 0.002) in the absence of significant group differences in online or offline learning over the three training days (p = 0.467 and p = 0.131). BLT resulted in transient down-regulation of H-reflex amplitude (Hmax/Mmax) in both test groups (p < 0.0001). However, the concurrent application of anodal-tsDCS with BLT elicited a longer lasting effect than sham-tsDCS + BLT (p = 0.050). Conclusion tsDCS improved locomotor skill acquisition and retention in healthy subjects and prolonged the physiological exercise-mediated downregulation of excitability of the alpha motoneuron pool. These results suggest that this strategy is worth exploring in neurorehabilitation of locomotor function." @default.
• W2912863036 created "2019-02-21" @default.
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• W2912863036 date "2019-05-01" @default.
• W2912863036 modified "2023-10-13" @default.
• W2912863036 title "Transcutaneous spinal direct current stimulation improves locomotor learning in healthy humans" @default.
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• W2912863036 cites W1534331654 @default.
• W2912863036 cites W167527184 @default.
• W2912863036 cites W1826908028 @default.
• W2912863036 cites W1868145307 @default.
• W2912863036 cites W1884902745 @default.
• W2912863036 cites W1963837902 @default.
• W2912863036 cites W1968884314 @default.
• W2912863036 cites W1970580671 @default.
• W2912863036 cites W1982751826 @default.
• W2912863036 cites W1987571446 @default.
• W2912863036 cites W1987677438 @default.
• W2912863036 cites W1989036618 @default.
• W2912863036 cites W1989243687 @default.
• W2912863036 cites W1997217328 @default.
• W2912863036 cites W2000780578 @default.
• W2912863036 cites W2005758226 @default.
• W2912863036 cites W2007592057 @default.
• W2912863036 cites W2008272581 @default.
• W2912863036 cites W2012137338 @default.
• W2912863036 cites W2012660043 @default.
• W2912863036 cites W2016956376 @default.
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• W2912863036 cites W2036898865 @default.
• W2912863036 cites W2040773973 @default.
• W2912863036 cites W2046747227 @default.
• W2912863036 cites W2051849293 @default.
• W2912863036 cites W2052572211 @default.
• W2912863036 cites W2055362996 @default.
• W2912863036 cites W2063972060 @default.
• W2912863036 cites W2064408790 @default.
• W2912863036 cites W2065300495 @default.
• W2912863036 cites W2088523814 @default.
• W2912863036 cites W2088882941 @default.
• W2912863036 cites W2090114646 @default.
• W2912863036 cites W2093308895 @default.
• W2912863036 cites W2097273459 @default.
• W2912863036 cites W2101287692 @default.
• W2912863036 cites W2102575454 @default.
• W2912863036 cites W2104711732 @default.
• W2912863036 cites W2105276489 @default.
• W2912863036 cites W2107009922 @default.
• W2912863036 cites W2108416046 @default.
• W2912863036 cites W2112448695 @default.
• W2912863036 cites W2115022547 @default.
• W2912863036 cites W2128591017 @default.
• W2912863036 cites W2129707336 @default.
• W2912863036 cites W2132862414 @default.
• W2912863036 cites W2142533684 @default.
• W2912863036 cites W2143864171 @default.
• W2912863036 cites W2144651233 @default.
• W2912863036 cites W2154103093 @default.
• W2912863036 cites W2158641331 @default.
• W2912863036 cites W2160326715 @default.
• W2912863036 cites W2162520805 @default.
• W2912863036 cites W2168550034 @default.
• W2912863036 cites W2180802550 @default.
• W2912863036 cites W2196778920 @default.
• W2912863036 cites W2297963168 @default.
• W2912863036 cites W2325098508 @default.
• W2912863036 cites W2335369791 @default.
• W2912863036 cites W2367151803 @default.
• W2912863036 cites W2462491535 @default.
• W2912863036 cites W2499062199 @default.
• W2912863036 cites W2530716013 @default.
• W2912863036 cites W2620236629 @default.
• W2912863036 cites W2717545635 @default.
• W2912863036 cites W2742924619 @default.
• W2912863036 cites W2750431169 @default.
• W2912863036 cites W2767129565 @default.
• W2912863036 cites W2794625595 @default.
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• W2912863036 doi "https://doi.org/10.1016/j.brs.2019.01.017" @default.
• W2912863036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7326485" @default.
• W2912863036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30733143" @default.
• W2912863036 hasPublicationYear "2019" @default.
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