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- W2912865065 endingPage "519" @default.
- W2912865065 startingPage "506" @default.
- W2912865065 abstract "Abstract Probiotics have shown great promise in promoting human health. Despite the promising evidence, there is little information on the clinical efficacy of many of the available probiotics and their mechanisms of action are often unclear. Bifidobacterium longum subsp. longum BB536 is a clinically effective, well-established, multifunctional probiotic that has a long history of human use in alleviating gastrointestinal, immunological and infectious diseases. This review summarizes the functional benefits of BB536 from the most relevant clinical and animal studies and offers a theoretical basis for understanding its mechanisms of action. Key clinical findings point out that BB536 could act as a microbiome modulator to orchestrate the physiological activities of gut communities. Specifically, BB536 modulates luminal metabolism, stabilizes gut microbiota, and ultimately drives a fine-tuned homeostatic balance within the host-microbiome interaction. Clinical evidence of effectiveness of BB536 and how such multifunctional activities take place would be valuable for an optimized probiotic selection." @default.
- W2912865065 created "2019-02-21" @default.
- W2912865065 creator A5008736482 @default.
- W2912865065 creator A5029225169 @default.
- W2912865065 creator A5051080925 @default.
- W2912865065 date "2019-03-01" @default.
- W2912865065 modified "2023-10-06" @default.
- W2912865065 title "Beneficial effects of Bifidobacterium longum subsp. longum BB536 on human health: Modulation of gut microbiome as the principal action" @default.
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