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- W2912870003 abstract "Myasthenia gravis is an autoimmune disease that commonly affects the palpebral and extraocular muscles. Ocular myasthenia gravis (OMG) is a variant of the disease that is confined to the ocular muscles but frequently becomes generalized over time. The diagnosis of OMG is often challenging but both clinical and laboratory findings are helpful in confirming the clinical suspicion. This review provides an update on the diagnostic approach and therapeutic options for OMG.Antimuscle-specific tyrosine kinase and LDL-related receptor-related protein 4 are newly available serologic testing for myasthenia gravis that can help in increasing the diagnostic sensitivity of OMG. They should be included to the diagnostic algorithm of OMG in appropriate clinical situations.OMG remains a primarily clinical diagnosis, but recent advances in laboratory testing can improve the diagnostic accuracy and should be used in appropriate clinical settings. The mainstay of treatment for OMG has not significantly changed over the past years, but the increasing availability of steroid-sparing agents improved the disease control while minimizing steroid-induced complications." @default.
- W2912870003 created "2019-02-21" @default.
- W2912870003 creator A5008020792 @default.
- W2912870003 creator A5052260050 @default.
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- W2912870003 date "2018-11-01" @default.
- W2912870003 modified "2023-10-11" @default.
- W2912870003 title "Ocular myasthenia gravis" @default.
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- W2912870003 doi "https://doi.org/10.1097/icu.0000000000000526" @default.
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