Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912871181> ?p ?o ?g. }
- W2912871181 abstract "Summary Excitatory neurons arising from a common progenitor establish radially-oriented clonal units in the neocortex which have been proposed to serve as elementary information processing modules. To characterize the cell types and circuit diagram within these clonal units, we performed single-cell RNA-sequencing and multi-cell patch clamp recordings of neurons derived from Nestin -positive progenitors. We found that radial clones do not appear to be fate-restricted, but instead individual clones are composed of a random sampling of the transcriptomic cell types present in a particular cortical area. The effect of lineage on synaptic connectivity depends on the type of connection tested: pairs of clonally related neurons were more likely to be connected vertically, across cortical layers, but not laterally within the same layer, compared to unrelated pairs. We propose that integration of vertical input from related neurons with lateral input from unrelated neurons may represent a developmentally programmed motif for assembling neocortical circuits." @default.
- W2912871181 created "2019-02-21" @default.
- W2912871181 creator A5011122432 @default.
- W2912871181 creator A5020622254 @default.
- W2912871181 creator A5022090269 @default.
- W2912871181 creator A5024450408 @default.
- W2912871181 creator A5036361185 @default.
- W2912871181 creator A5043130208 @default.
- W2912871181 creator A5045223218 @default.
- W2912871181 creator A5049159760 @default.
- W2912871181 creator A5054637446 @default.
- W2912871181 creator A5061084605 @default.
- W2912871181 creator A5066531533 @default.
- W2912871181 creator A5077749659 @default.
- W2912871181 date "2019-01-23" @default.
- W2912871181 modified "2023-09-30" @default.
- W2912871181 title "Cell type composition and circuit organization of neocortical radial clones" @default.
- W2912871181 cites W1487222554 @default.
- W2912871181 cites W1489264149 @default.
- W2912871181 cites W1503727145 @default.
- W2912871181 cites W1559406855 @default.
- W2912871181 cites W1606181492 @default.
- W2912871181 cites W1916653587 @default.
- W2912871181 cites W1942860519 @default.
- W2912871181 cites W1973654985 @default.
- W2912871181 cites W1976084841 @default.
- W2912871181 cites W1979283544 @default.
- W2912871181 cites W1979952856 @default.
- W2912871181 cites W1981164058 @default.
- W2912871181 cites W1981958858 @default.
- W2912871181 cites W1982562003 @default.
- W2912871181 cites W1985893327 @default.
- W2912871181 cites W2001453133 @default.
- W2912871181 cites W2002687566 @default.
- W2912871181 cites W2008239861 @default.
- W2912871181 cites W2009311165 @default.
- W2912871181 cites W2009742334 @default.
- W2912871181 cites W2011525418 @default.
- W2912871181 cites W2014782492 @default.
- W2912871181 cites W2019552331 @default.
- W2912871181 cites W2025625968 @default.
- W2912871181 cites W2026863186 @default.
- W2912871181 cites W2036981746 @default.
- W2912871181 cites W2037338370 @default.
- W2912871181 cites W2045233939 @default.
- W2912871181 cites W2052790148 @default.
- W2912871181 cites W2056661320 @default.
- W2912871181 cites W2062450961 @default.
- W2912871181 cites W2063620761 @default.
- W2912871181 cites W2063634360 @default.
- W2912871181 cites W2065286706 @default.
- W2912871181 cites W2068767807 @default.
- W2912871181 cites W2077576885 @default.
- W2912871181 cites W2093712120 @default.
- W2912871181 cites W2103087308 @default.
- W2912871181 cites W2103423972 @default.
- W2912871181 cites W2103934527 @default.
- W2912871181 cites W2110513111 @default.
- W2912871181 cites W2121005041 @default.
- W2912871181 cites W2125462953 @default.
- W2912871181 cites W2127136880 @default.
- W2912871181 cites W2130793535 @default.
- W2912871181 cites W2135369850 @default.
- W2912871181 cites W2140591465 @default.
- W2912871181 cites W2142826449 @default.
- W2912871181 cites W2149573463 @default.
- W2912871181 cites W2156728993 @default.
- W2912871181 cites W2166643198 @default.
- W2912871181 cites W2195364602 @default.
- W2912871181 cites W2231058499 @default.
- W2912871181 cites W2267554996 @default.
- W2912871181 cites W2268971953 @default.
- W2912871181 cites W2513966415 @default.
- W2912871181 cites W2558207675 @default.
- W2912871181 cites W2589689453 @default.
- W2912871181 cites W2769765726 @default.
- W2912871181 cites W2772624269 @default.
- W2912871181 cites W2800093856 @default.
- W2912871181 cites W2891756221 @default.
- W2912871181 cites W2950976066 @default.
- W2912871181 cites W4211203356 @default.
- W2912871181 doi "https://doi.org/10.1101/526681" @default.
- W2912871181 hasPublicationYear "2019" @default.
- W2912871181 type Work @default.
- W2912871181 sameAs 2912871181 @default.
- W2912871181 citedByCount "4" @default.
- W2912871181 countsByYear W29128711812019 @default.
- W2912871181 countsByYear W29128711812020 @default.
- W2912871181 countsByYear W29128711812021 @default.
- W2912871181 crossrefType "posted-content" @default.
- W2912871181 hasAuthorship W2912871181A5011122432 @default.
- W2912871181 hasAuthorship W2912871181A5020622254 @default.
- W2912871181 hasAuthorship W2912871181A5022090269 @default.
- W2912871181 hasAuthorship W2912871181A5024450408 @default.
- W2912871181 hasAuthorship W2912871181A5036361185 @default.
- W2912871181 hasAuthorship W2912871181A5043130208 @default.
- W2912871181 hasAuthorship W2912871181A5045223218 @default.
- W2912871181 hasAuthorship W2912871181A5049159760 @default.
- W2912871181 hasAuthorship W2912871181A5054637446 @default.
- W2912871181 hasAuthorship W2912871181A5061084605 @default.