Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912880143> ?p ?o ?g. }
- W2912880143 endingPage "195" @default.
- W2912880143 startingPage "185" @default.
- W2912880143 abstract "This chapter summarizes recommendations on important aspects of the management of patients with severe malaria and severe dengue. Severe falciparum malaria requires rapid parasitological diagnosis by microscopy or rapid diagnostic test (RCT) and prompt initiation of parenteral artesunate. Fluid bolus therapy should be avoided in patients without hypotensive shock, and we suggest initial (24 h) crystalloid fluid therapy of 2–4 mL/kg/h, which may subsequently be reduced to 1 mL/kg/h in patients receiving additional fluids, e.g., through enteral tube feeding. In the minority of those patients presenting with hypotensive shock, we suggest fluid bolus therapy (30 mL/kg) with an isotonic crystalloid and early initiation of vasopressor support. Enteral feeding in non-intubated adult patients with cerebral malaria can start after 60 h, to avoid aspiration pneumonia. There are insufficient data to suggest this in pediatric cerebral malaria. The diagnosis of severe dengue is commonly with a combined dengue antigen (NS1) and antibody RDT. No antiviral treatment is currently available. Dengue shock results from capillary leakage, although hemorrhage or depression of myocardial contractility can contribute. The World Health Organization guidelines recommend restoration of the circulation guided by pulse pressure, capillary refill time, hematocrit, and urine output. Large (>15 mL/kg) rapid (<30 min) fluid boluses should be avoided, but prompt fluid administration with crystalloids is essential and should be restricted as soon as the critical phase is over to avoid pulmonary edema. Corticosteroids are not recommended, neither is platelet transfusion for thrombocytopenia in the absence of active bleeding or other risk factors." @default.
- W2912880143 created "2019-02-21" @default.
- W2912880143 creator A5005250831 @default.
- W2912880143 creator A5007302507 @default.
- W2912880143 creator A5007697425 @default.
- W2912880143 creator A5013315693 @default.
- W2912880143 creator A5037866671 @default.
- W2912880143 creator A5048152610 @default.
- W2912880143 creator A5051325334 @default.
- W2912880143 creator A5051408897 @default.
- W2912880143 creator A5058604300 @default.
- W2912880143 date "2019-01-01" @default.
- W2912880143 modified "2023-09-23" @default.
- W2912880143 title "Management of Severe Malaria and Severe Dengue in Resource-Limited Settings" @default.
- W2912880143 cites W1529579185 @default.
- W2912880143 cites W1712614766 @default.
- W2912880143 cites W184931957 @default.
- W2912880143 cites W1993432467 @default.
- W2912880143 cites W1996379835 @default.
- W2912880143 cites W2000803055 @default.
- W2912880143 cites W2012594970 @default.
- W2912880143 cites W2048245345 @default.
- W2912880143 cites W2050003410 @default.
- W2912880143 cites W2062426071 @default.
- W2912880143 cites W2062710309 @default.
- W2912880143 cites W2074752109 @default.
- W2912880143 cites W2080824822 @default.
- W2912880143 cites W2088104130 @default.
- W2912880143 cites W2093008801 @default.
- W2912880143 cites W2096816967 @default.
- W2912880143 cites W2096883458 @default.
- W2912880143 cites W2108788182 @default.
- W2912880143 cites W2112195038 @default.
- W2912880143 cites W2118846793 @default.
- W2912880143 cites W2122219746 @default.
- W2912880143 cites W2129812354 @default.
- W2912880143 cites W2132269368 @default.
- W2912880143 cites W2147976206 @default.
- W2912880143 cites W2148802878 @default.
- W2912880143 cites W2149691922 @default.
- W2912880143 cites W2159451467 @default.
- W2912880143 cites W2162331185 @default.
- W2912880143 cites W2164499679 @default.
- W2912880143 cites W2165056787 @default.
- W2912880143 cites W2168412520 @default.
- W2912880143 cites W2175122437 @default.
- W2912880143 cites W2226587177 @default.
- W2912880143 cites W2442246762 @default.
- W2912880143 cites W2950420258 @default.
- W2912880143 cites W4211101162 @default.
- W2912880143 cites W4211136995 @default.
- W2912880143 cites W4296586445 @default.
- W2912880143 doi "https://doi.org/10.1007/978-3-030-03143-5_9" @default.
- W2912880143 hasPublicationYear "2019" @default.
- W2912880143 type Work @default.
- W2912880143 sameAs 2912880143 @default.
- W2912880143 citedByCount "1" @default.
- W2912880143 countsByYear W29128801432021 @default.
- W2912880143 crossrefType "book-chapter" @default.
- W2912880143 hasAuthorship W2912880143A5005250831 @default.
- W2912880143 hasAuthorship W2912880143A5007302507 @default.
- W2912880143 hasAuthorship W2912880143A5007697425 @default.
- W2912880143 hasAuthorship W2912880143A5013315693 @default.
- W2912880143 hasAuthorship W2912880143A5037866671 @default.
- W2912880143 hasAuthorship W2912880143A5048152610 @default.
- W2912880143 hasAuthorship W2912880143A5051325334 @default.
- W2912880143 hasAuthorship W2912880143A5051408897 @default.
- W2912880143 hasAuthorship W2912880143A5058604300 @default.
- W2912880143 hasBestOaLocation W29128801431 @default.
- W2912880143 hasConcept C126322002 @default.
- W2912880143 hasConcept C141071460 @default.
- W2912880143 hasConcept C177713679 @default.
- W2912880143 hasConcept C203014093 @default.
- W2912880143 hasConcept C2776468924 @default.
- W2912880143 hasConcept C2777714996 @default.
- W2912880143 hasConcept C2778048844 @default.
- W2912880143 hasConcept C2778059366 @default.
- W2912880143 hasConcept C2778371730 @default.
- W2912880143 hasConcept C2781300812 @default.
- W2912880143 hasConcept C2909332496 @default.
- W2912880143 hasConcept C42219234 @default.
- W2912880143 hasConcept C43376680 @default.
- W2912880143 hasConcept C533803919 @default.
- W2912880143 hasConcept C71924100 @default.
- W2912880143 hasConcept C84393581 @default.
- W2912880143 hasConceptScore W2912880143C126322002 @default.
- W2912880143 hasConceptScore W2912880143C141071460 @default.
- W2912880143 hasConceptScore W2912880143C177713679 @default.
- W2912880143 hasConceptScore W2912880143C203014093 @default.
- W2912880143 hasConceptScore W2912880143C2776468924 @default.
- W2912880143 hasConceptScore W2912880143C2777714996 @default.
- W2912880143 hasConceptScore W2912880143C2778048844 @default.
- W2912880143 hasConceptScore W2912880143C2778059366 @default.
- W2912880143 hasConceptScore W2912880143C2778371730 @default.
- W2912880143 hasConceptScore W2912880143C2781300812 @default.
- W2912880143 hasConceptScore W2912880143C2909332496 @default.
- W2912880143 hasConceptScore W2912880143C42219234 @default.
- W2912880143 hasConceptScore W2912880143C43376680 @default.