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• W2912882758 endingPage "1249" @default.
• W2912882758 startingPage "1243" @default.
• W2912882758 abstract "The growing resistance of pathogens to conventional antibiotics has become a public health problem requiring novel effective solutions. In this context, metal-organic frameworks (MOFs) are attracting attention because they can act as reservoirs releasing metal ions with antibacterial properties. This action is reminiscent of that proposed for metal- and metal oxide-nanoparticles but different from the action of antibiotics. These features make MOFs promising candidates for pharmaceutical and biomedical applications. Here, IRMOF-3 was modified with 2,5-dimethoxytetrahydrofuran, N,N′-disuccinimidyl carbonate, acryloyl chloride, and phthalaldehyde to produce, respectively, IRMOF-3-FU, IRMOF-3-SU, IRMOF-3-AC, IRMOF-3-DL in 38 to 90 % yields. Remarkably, the biological activity of these compounds evaluated against various bacterial and fungal strains is higher than the activity of commercial antibiotics." @default.
• W2912882758 created "2019-02-21" @default.
• W2912882758 creator A5000169107 @default.
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• W2912882758 date "2019-02-20" @default.
• W2912882758 modified "2023-10-16" @default.
• W2912882758 title "IRMOF‐3 Biological Activity Enhancement by Post‐Synthetic Modification" @default.
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• W2912882758 doi "https://doi.org/10.1002/ejic.201801442" @default.
• W2912882758 hasPublicationYear "2019" @default.
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