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• W2912887986 abstract "Summary 1.An analysis of forty-one cases of leucemia observed at the Children's Memorial Hospital emphasizes the similarities between childhood leucemia and a disease of an infectious nature. Forty-eight and seven-tenths per cent of the group gave a history of a known antecedent infection, preceding the onset of leucemic symptoms. The incidence of antecedent infections was highest among those cases whose early course was aleucemic. 2.Three common clinical types are discussed: Type I, the course of which is fulminating and the clinical and the hematologic features of which are classical. Type II, the course of which is less rapidly fatal, and the clinical and the hematologic aspects of which are more easily confused with leucemoid states or other disorders of the hemopoietic system. Type III, the course of which is characterized by prolonged period of illness marked by the occurrence of remissions and exacerbations and a fluctuating blood picture. The aleucemic phase of this group has certain clinical and pathologic features in common with malignant neutropenia. Summary 1.An analysis of forty-one cases of leucemia observed at the Children's Memorial Hospital emphasizes the similarities between childhood leucemia and a disease of an infectious nature. Forty-eight and seven-tenths per cent of the group gave a history of a known antecedent infection, preceding the onset of leucemic symptoms. The incidence of antecedent infections was highest among those cases whose early course was aleucemic. 2.Three common clinical types are discussed: Type I, the course of which is fulminating and the clinical and the hematologic features of which are classical. Type II, the course of which is less rapidly fatal, and the clinical and the hematologic aspects of which are more easily confused with leucemoid states or other disorders of the hemopoietic system. Type III, the course of which is characterized by prolonged period of illness marked by the occurrence of remissions and exacerbations and a fluctuating blood picture. The aleucemic phase of this group has certain clinical and pathologic features in common with malignant neutropenia." @default.
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• W2912887986 date "1936-01-01" @default.
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• W2912887986 title "Childhood leucemia" @default.
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• W2912887986 doi "https://doi.org/10.1016/s0022-3476(36)80214-5" @default.
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