FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912889396> ?p ?o ?g. }

• W2912889396 endingPage "2959" @default.
• W2912889396 startingPage "2949" @default.
• W2912889396 abstract "The porinACj is an α-helical porin that spans the mycolic acid outer membrane of Gram-positive mycolate, Corynebacterium jeikeium. Here, we report that a 40-amino acid, synthetic peptide, pPorA corresponding to porin PorACj, inserts into the lipid bilayers and forms well-defined pores. By electrical recordings, we measured the single-channel properties that revealed the autonomous assembly of large conductance ion-selective synthetic pores. Further, we characterized the functional properties by blocking the peptide pores by cyclodextrins of different charge and symmetry. We deduced the subunit stoichiometry and putative structure of the pore by site-specific chemical modification in single-channel electrical recordings and gel electrophoresis. On the basis of these findings, we suggest that this is a large functional uniform transmembrane pore built entirely from short synthetic α-helical peptides. Accordingly, we propose a model demonstrating structural assembly of large α-helix-based peptide pores for understanding the action of antimicrobial peptides and for the design of pores with applications in biotechnology." @default.
• W2912889396 created "2019-02-21" @default.
• W2912889396 creator A5003972683 @default.
• W2912889396 creator A5013223227 @default.
• W2912889396 creator A5013881860 @default.
• W2912889396 creator A5019332741 @default.
• W2912889396 creator A5040136367 @default.
• W2912889396 creator A5043041371 @default.
• W2912889396 date "2019-01-31" @default.
• W2912889396 modified "2023-10-08" @default.
• W2912889396 title "Autonomously Assembled Synthetic Transmembrane Peptide Pore" @default.
• W2912889396 cites W1560197628 @default.
• W2912889396 cites W1592730805 @default.
• W2912889396 cites W1803935349 @default.
• W2912889396 cites W1944771822 @default.
• W2912889396 cites W1969583827 @default.
• W2912889396 cites W1972209638 @default.
• W2912889396 cites W1974312616 @default.
• W2912889396 cites W1989998611 @default.
• W2912889396 cites W1997868832 @default.
• W2912889396 cites W1999646223 @default.
• W2912889396 cites W2008451855 @default.
• W2912889396 cites W2014226560 @default.
• W2912889396 cites W2036087614 @default.
• W2912889396 cites W2038218701 @default.
• W2912889396 cites W2053457342 @default.
• W2912889396 cites W2054127621 @default.
• W2912889396 cites W2054602599 @default.
• W2912889396 cites W2058856302 @default.
• W2912889396 cites W2070441707 @default.
• W2912889396 cites W2073283522 @default.
• W2912889396 cites W2079415210 @default.
• W2912889396 cites W2084845164 @default.
• W2912889396 cites W2094207537 @default.
• W2912889396 cites W2097099115 @default.
• W2912889396 cites W2098912817 @default.
• W2912889396 cites W2100077230 @default.
• W2912889396 cites W2105546584 @default.
• W2912889396 cites W2114539124 @default.
• W2912889396 cites W2127407003 @default.
• W2912889396 cites W2134778179 @default.
• W2912889396 cites W2148306017 @default.
• W2912889396 cites W2151164439 @default.
• W2912889396 cites W2153099927 @default.
• W2912889396 cites W2159861471 @default.
• W2912889396 cites W2161696543 @default.
• W2912889396 cites W2165642493 @default.
• W2912889396 cites W2173280871 @default.
• W2912889396 cites W2195753589 @default.
• W2912889396 cites W2217370284 @default.
• W2912889396 cites W2259815689 @default.
• W2912889396 cites W2288926314 @default.
• W2912889396 cites W2329887558 @default.
• W2912889396 cites W2342925174 @default.
• W2912889396 cites W2517219039 @default.
• W2912889396 cites W2523550430 @default.
• W2912889396 cites W2524992726 @default.
• W2912889396 cites W2549678059 @default.
• W2912889396 cites W2562252980 @default.
• W2912889396 cites W2579233876 @default.
• W2912889396 cites W2584282544 @default.
• W2912889396 cites W2731130386 @default.
• W2912889396 cites W2790686372 @default.
• W2912889396 cites W2804651513 @default.
• W2912889396 cites W4239562974 @default.
• W2912889396 cites W834977926 @default.
• W2912889396 doi "https://doi.org/10.1021/jacs.8b09973" @default.
• W2912889396 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30702873" @default.
• W2912889396 hasPublicationYear "2019" @default.
• W2912889396 type Work @default.
• W2912889396 sameAs 2912889396 @default.
• W2912889396 citedByCount "29" @default.
• W2912889396 countsByYear W29128893962019 @default.
• W2912889396 countsByYear W29128893962020 @default.
• W2912889396 countsByYear W29128893962021 @default.
• W2912889396 countsByYear W29128893962022 @default.
• W2912889396 countsByYear W29128893962023 @default.
• W2912889396 crossrefType "journal-article" @default.
• W2912889396 hasAuthorship W2912889396A5003972683 @default.
• W2912889396 hasAuthorship W2912889396A5013223227 @default.
• W2912889396 hasAuthorship W2912889396A5013881860 @default.
• W2912889396 hasAuthorship W2912889396A5019332741 @default.
• W2912889396 hasAuthorship W2912889396A5040136367 @default.
• W2912889396 hasAuthorship W2912889396A5043041371 @default.
• W2912889396 hasConcept C104317684 @default.
• W2912889396 hasConcept C12554922 @default.
• W2912889396 hasConcept C146587185 @default.
• W2912889396 hasConcept C170493617 @default.
• W2912889396 hasConcept C171250308 @default.
• W2912889396 hasConcept C185592680 @default.
• W2912889396 hasConcept C192562407 @default.
• W2912889396 hasConcept C21951064 @default.
• W2912889396 hasConcept C24530287 @default.
• W2912889396 hasConcept C2777317804 @default.
• W2912889396 hasConcept C2779281246 @default.
• W2912889396 hasConcept C39944091 @default.
• W2912889396 hasConcept C41625074 @default.
• W2912889396 hasConcept C50254741 @default.

• next