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• W2912891971 abstract "Objective: The American College of Radiology updated the terms used for expressing the imaging characteristics of non-mass enhancement (NME) lesions in the fifth edition of the breast imaging-reporting data system (BI-RADS) lexicon. Both the distribution and internal enhancement descriptors were revised for NME lesions. Our aim was to determine the MRI characteristics of NME lesions and to investigate their association with malignancy. Methods: The MRI results of 129 NME lesions were retrospectively evaluated. The medical files, biopsy results and follow-up findings of lesions were recorded. Patients who had benign biopsy and those who had stable or regressed lesions during follow-up were classified as benign. All MRI results had been obtained with a 1.5 Tesla Signa HDx MR system (GE Healthcare). Results: Segmental and diffuse distribution along with clustered-ring internal enhancement were significantly associated with malignancy, while linear distribution and homogeneous enhancement pattern were associated with benignancy. Additionally, the plateau type (Type II) curve was significantly more frequent in malignant lesions. There was no association between the presence of cystic structures and the benign/malignant nature of the lesion. However, multivariate logistic regression showed that only segmental distribution and diffusion restriction were associated with malignancy. Conclusion: In the current study, segmental distribution, clustered-ring enhancement, Type II dynamic curve and the presence of diffusion restriction were found to be associated with malignancy. There is a requirement for multicenter studies which include higher numbers of patients in order to better evaluate lesions with rarer characteristics for distribution and enhancement pattern. Advances in knowledge: Our aim in this study was to investigate the MRI characteristics of NME lesions. We have reported the MRI findings of NME lesions and have found that segmental distribution and clustered-ring enhancement patterns are significantly more frequent in malignant lesions." @default.
• W2912891971 created "2019-02-21" @default.
• W2912891971 creator A5028431314 @default.
• W2912891971 date "2019-04-01" @default.
• W2912891971 modified "2023-10-16" @default.
• W2912891971 title "The MRI characteristics of non-mass enhancement lesions of the breast: associations with malignancy" @default.
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• W2912891971 doi "https://doi.org/10.1259/bjr.20180464" @default.
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