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- W2912919938 abstract "Cytochrome (CYP) P450s are a superfamily of enzymes that detoxify xenobiotics and regulate numerous physiological processes in insects. The genomes of phytophagous insects usually contain large numbers of P450s, especially within the CYP3 clan. Within this clan, CYP6 subfamily members help detoxify plant host secondary metabolites. In this study, we analyzed three CYP6 genes in the highly polyphagous invasive pest, Halyomorpha halys (Stål), commonly known as brown marmorated stink bug. We characterized and validated the expression of HhCYP6BQ27, HhCYP6BK13, and HhCYP6BK24 among sexes, tissues (gut, fat body, and Malpighian tubules) and hosts (apple, corn, soybean). Sequence characterization by amino acid alignments confirmed the presence of conserved motifs typical of the P450 superfamily. No significant differences existed in gene expression among sexes or when fed different hosts, suggesting that these transcripts might have broad substrate specificities. However, significant differences in gene expression were observed among the tissues studied and were gene-dependent. Collectively, the results show that H. halys differentially expressed CYP6 genes among tissues, which may be related to important and specific physiological functions. This study has increased our understanding of H. halys biology that can be useful for functional studies and can potentially be exploited in developing sustainable pest management strategies." @default.
- W2912919938 created "2019-02-21" @default.
- W2912919938 creator A5023818060 @default.
- W2912919938 creator A5038419161 @default.
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- W2912919938 date "2019-02-10" @default.
- W2912919938 modified "2023-10-13" @default.
- W2912919938 title "Differential Expression of Cytochrome P450 CYP6 Genes in the Brown Marmorated Stink Bug, Halyomorpha halys (Hemiptera: Pentatomidae)" @default.
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- W2912919938 doi "https://doi.org/10.1093/jee/toz007" @default.
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