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- W2912941833 abstract "Abstract Background The aims of this meta-analysis are (i) to estimate the pooled relative risk (RR) of developing non-affective psychotic disorder (NAPD) and affective psychotic disorder (APD) among migrants and their children; (ii) to adjust these results for socioeconomic status (SES); (iii) to examine the sources of heterogeneity that underlie the risk of NAPD. Methods We included population-based incidence studies that reported an age-adjusted RR with 95% confidence interval (CI) published 1 January 1977–12 October 2017 and used a random-effects model. Results We retrieved studies performed in Europe ( n = 43), Israel ( n = 3), Canada ( n = 2) and Australia ( n = 1). The meta-analysis yielded a RR, adjusted for age and sex, of 2.13 (95% CI 1.99–2.27) for NAPD and 2.94 (95% CI 2.28–3.79) for APD. The RRs diminished, but persisted after adjustment for SES. With reference to NAPD: a personal or parental history of migration to Europe from countries outside Europe was associated with a higher RR (RR = 2.94, 95% CI 2.63–3.29) than migration within Europe (RR = 1.88, 95% 1.62–2.18). The corresponding RR was lower in Israel (RR = 1.22; 0.99–1.50) and Canada (RR = 1.21; 0.85–1.74). The RR was highest among individuals with a black skin colour (RR = 4.19, 95% CI 3.42–5.14). The evidence of a difference in risk between first and second generation was insufficient. Conclusions Positive selection may explain the low risk in Canada, while the change from exclusion to inclusion may do the same in Israel. Given the high risks among migrants from developing countries in Europe, social exclusion may have a pathogenic role." @default.
- W2912941833 created "2019-02-21" @default.
- W2912941833 creator A5059592366 @default.
- W2912941833 creator A5074901371 @default.
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- W2912941833 date "2019-02-06" @default.
- W2912941833 modified "2023-10-16" @default.
- W2912941833 title "Migration and psychosis: a meta-analysis of incidence studies" @default.
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- W2912941833 doi "https://doi.org/10.1017/s0033291719000035" @default.
- W2912941833 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7083571" @default.
- W2912941833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30722795" @default.
- W2912941833 hasPublicationYear "2019" @default.
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