Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912956073> ?p ?o ?g. }
- W2912956073 endingPage "509" @default.
- W2912956073 startingPage "501" @default.
- W2912956073 abstract "Mortality from pediatric sepsis has steadily declined over the past several decades; however, little is known about morbidity among survivors. We aimed to determine the prevalence of and risk factors for failure to recover to baseline health-related quality of life following community-acquired pediatric sepsis.Retrospective cohort study.Seattle Children's Hospital.Children aged 1 month to 21 years admitted to the inpatient wards or ICUs from 2012 to 2015 who met 2005 consensus sepsis criteria within 4 hours of hospitalization and were enrolled in the hospital's Outcomes Assessment Program with baseline, admission, and post-discharge health-related quality of life data available.None.We assessed health-related quality of life with the Pediatric Quality of Life Inventory for pre-admission baseline, admission, and post-discharge (median, 31 d) status. We determined associations between patient and illness characteristics with failure to recover within 4.5 points of baseline at follow-up (the minimum clinically significant difference between two scores). Of 790 patients, 23.8% failed to recover to baseline health-related quality of life at follow-up. Factors associated with failure to recover were septic shock, older age, private insurance, complex chronic disease, immune compromise, CNS infection or bacteremia, ICU admission, and longer length of stay. On multivariable analysis controlling for time to follow-up, failure to recover was independently associated with septic shock (relative risk, 1.79; 95% CI, 1.24-2.58), older age (relative risk, 1.02/yr; 95% CI, 1.01-1.05), immune compromise (relative risk, 1.83; 95% CI, 1.40-2.40), and length of stay (relative risk, 1.03/d; 95% CI, 1.01-1.04).Nearly one-quarter of children surviving hospitalization for community-acquired sepsis experienced a clinically significant deterioration in health-related quality of life. We identify risk factors for poor outcomes following sepsis and highlight the need for ongoing evaluation and treatment by primary and specialty care providers for pediatric sepsis survivors after hospital discharge." @default.
- W2912956073 created "2019-02-21" @default.
- W2912956073 creator A5020173242 @default.
- W2912956073 creator A5053206265 @default.
- W2912956073 creator A5053266553 @default.
- W2912956073 creator A5064694471 @default.
- W2912956073 creator A5080966483 @default.
- W2912956073 date "2019-06-01" @default.
- W2912956073 modified "2023-10-16" @default.
- W2912956073 title "Health-Related Quality of Life Among Survivors of Pediatric Sepsis*" @default.
- W2912956073 cites W1818600552 @default.
- W2912956073 cites W192011221 @default.
- W2912956073 cites W1963906926 @default.
- W2912956073 cites W1977179251 @default.
- W2912956073 cites W1977420311 @default.
- W2912956073 cites W1978586171 @default.
- W2912956073 cites W1978997971 @default.
- W2912956073 cites W1988148664 @default.
- W2912956073 cites W2005347463 @default.
- W2912956073 cites W2011693957 @default.
- W2912956073 cites W2018763717 @default.
- W2912956073 cites W2019778131 @default.
- W2912956073 cites W2024356331 @default.
- W2912956073 cites W2025430639 @default.
- W2912956073 cites W2032651303 @default.
- W2912956073 cites W2035376333 @default.
- W2912956073 cites W2044356534 @default.
- W2912956073 cites W2050042549 @default.
- W2912956073 cites W2050878694 @default.
- W2912956073 cites W2052233685 @default.
- W2912956073 cites W2055033406 @default.
- W2912956073 cites W2063790661 @default.
- W2912956073 cites W2070447329 @default.
- W2912956073 cites W2076590961 @default.
- W2912956073 cites W2084445380 @default.
- W2912956073 cites W2131479410 @default.
- W2912956073 cites W2136271495 @default.
- W2912956073 cites W2138584458 @default.
- W2912956073 cites W2160697538 @default.
- W2912956073 cites W2160746124 @default.
- W2912956073 cites W2323149989 @default.
- W2912956073 cites W2331166889 @default.
- W2912956073 cites W2417098872 @default.
- W2912956073 cites W2480877943 @default.
- W2912956073 cites W2520212960 @default.
- W2912956073 cites W2573419356 @default.
- W2912956073 cites W4234050204 @default.
- W2912956073 cites W4380185495 @default.
- W2912956073 cites W4385244800 @default.
- W2912956073 cites W3147232110 @default.
- W2912956073 doi "https://doi.org/10.1097/pcc.0000000000001886" @default.
- W2912956073 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6548660" @default.
- W2912956073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30720672" @default.
- W2912956073 hasPublicationYear "2019" @default.
- W2912956073 type Work @default.
- W2912956073 sameAs 2912956073 @default.
- W2912956073 citedByCount "43" @default.
- W2912956073 countsByYear W29129560732019 @default.
- W2912956073 countsByYear W29129560732020 @default.
- W2912956073 countsByYear W29129560732021 @default.
- W2912956073 countsByYear W29129560732022 @default.
- W2912956073 countsByYear W29129560732023 @default.
- W2912956073 crossrefType "journal-article" @default.
- W2912956073 hasAuthorship W2912956073A5020173242 @default.
- W2912956073 hasAuthorship W2912956073A5053206265 @default.
- W2912956073 hasAuthorship W2912956073A5053266553 @default.
- W2912956073 hasAuthorship W2912956073A5064694471 @default.
- W2912956073 hasAuthorship W2912956073A5080966483 @default.
- W2912956073 hasBestOaLocation W29129560732 @default.
- W2912956073 hasConcept C126322002 @default.
- W2912956073 hasConcept C159110408 @default.
- W2912956073 hasConcept C167135981 @default.
- W2912956073 hasConcept C177713679 @default.
- W2912956073 hasConcept C187212893 @default.
- W2912956073 hasConcept C194828623 @default.
- W2912956073 hasConcept C201903717 @default.
- W2912956073 hasConcept C2777628635 @default.
- W2912956073 hasConcept C2778384902 @default.
- W2912956073 hasConcept C2779443120 @default.
- W2912956073 hasConcept C2779951463 @default.
- W2912956073 hasConcept C501593827 @default.
- W2912956073 hasConcept C71924100 @default.
- W2912956073 hasConcept C72563966 @default.
- W2912956073 hasConcept C86803240 @default.
- W2912956073 hasConcept C89423630 @default.
- W2912956073 hasConceptScore W2912956073C126322002 @default.
- W2912956073 hasConceptScore W2912956073C159110408 @default.
- W2912956073 hasConceptScore W2912956073C167135981 @default.
- W2912956073 hasConceptScore W2912956073C177713679 @default.
- W2912956073 hasConceptScore W2912956073C187212893 @default.
- W2912956073 hasConceptScore W2912956073C194828623 @default.
- W2912956073 hasConceptScore W2912956073C201903717 @default.
- W2912956073 hasConceptScore W2912956073C2777628635 @default.
- W2912956073 hasConceptScore W2912956073C2778384902 @default.
- W2912956073 hasConceptScore W2912956073C2779443120 @default.
- W2912956073 hasConceptScore W2912956073C2779951463 @default.
- W2912956073 hasConceptScore W2912956073C501593827 @default.
- W2912956073 hasConceptScore W2912956073C71924100 @default.