FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912961005> ?p ?o ?g. }

• W2912961005 endingPage "S479" @default.
• W2912961005 startingPage "S477" @default.
• W2912961005 abstract "Introduction: One new endoscopic classification of esophageal mucosa in achalasia (EMIA) was proposed in 2015, but the clinical significance is unclear. The aim of this study was to investigate the predicting ability of the EMIA classification for submucosal fibrosis affecting the success of peroral endoscopic myotomy (POEM). Methods: The endoscopic and clinical data of patients undergoing POEM from 2012 to 2016 was investigated retrospectively. According to the endoscopic pictures or videos, the EMIA classification (from grade a to f, Figure 1), and submucosal fibrosis (SMF) classification (from grade 0 to 4, Figure 2) were recorded. The baseline characteristics, including previous treatment history and Ling classification, were obtained from clinical and endoscopic records. Then the relation of EMIA and SMF gradings was assessed by Spearman's rank correlation, and the risk factors of submucosal fibrosis were identified by logistic regression analysis.Figure: EMIA classification under endoscopy: a, the mucosa is norma with clear vasular; b, the mucosa is rough with vague vascular; c, the mucosa is granular without obvious vascular texture; d, the mucosa is pachyntic, striated or likes sulcus; e, ulcer in the mucosa; d, scar in the mucosa. Grade e and d are recorded as the four grading according to the involvment of esophageal circmference: 1. ulcer/scar≤1/4; 2. 1/4<ulcer/scar≤1/2; 3. 1/2< ulcer/scar≤3/4; 4. ulcer/scar >3/4.Figure: SMF classification after submucosal injection: a, SMF-0 (no fibrosis), the fibrous filaments are found to be dispersed throughout the transparent submucosal layer, and the mucosa is easy to be lifted; b, SMF-1 (mild fibrosis), the fibers are grouped in bundles in the submucosal layer, and the mucosa can be lifted; c, SMF-2 (moderate fibrosis), the inregular fibers merge with each other in the lower transparent submucosa, and the lifting effect is less; d, SMF-2 (severe fibrosis), the mucosa is completely adhered to the muscularis propria and the lifting effect is negative.Results: A total of 564 patients (267 males and 297 females, mean age 43 years) with achalasia was performed with POEM were enrolled. For EMIA classification, there was 40 (7.1%), 373(66.1%), 139(24.6%), 10(1.8%), 1(0.2%), 1(0.2%) for grade a, b, c, d, e1 and f4 respectively. POEM was not completed for 11 cases because of excessive submucosal fibrosis preventing submucosal tunneling. There was Because grades e-f were rare and the related submucosal fibrosis was obvious, these two grading cases were excluded from the following fibrosis correlation analysis. Correlation between EMIA (from a to d) and SMF grading was significant (r=0.61, P < 0.01). Multivariate logistic analysis, including age, gender, course, Ling classification, previous treatment and EMIA classification, showed that the EMIA classification (P < 0.01) and previous treatment (POEM and surgery, P=0.037) were the risk factors for submucosal fibrosis; the EMIA classification was the only influencing factor for successful operation of POEM (P < 0.01). Conclusion: The new endoscopic EMIA classification is one predictor for the degree of submucosal fibrosis, and may be used for assessment of the difficulty and success of POEM. Additional prospective studies on this new classification are required to confirm its clinical significance.Table: Table. Baseline characteristics of the enrolled patientsFigure: Different degree of submucosa fibrosis in EMIA-a to EMIA-d: a positive correlation between EMIA and SMF grading." @default.
• W2912961005 created "2019-02-21" @default.
• W2912961005 creator A5037547064 @default.
• W2912961005 creator A5037599773 @default.
• W2912961005 creator A5069691488 @default.
• W2912961005 creator A5087752080 @default.
• W2912961005 date "2017-10-01" @default.
• W2912961005 modified "2023-09-27" @default.
• W2912961005 title "New Endoscopic Classification of Esophageal Mucosa in Achalasia: A Predictor for Submucosal Fibrosis: 2017 Presidential Poster Award" @default.
• W2912961005 doi "https://doi.org/10.14309/00000434-201710001-00846" @default.
• W2912961005 hasPublicationYear "2017" @default.
• W2912961005 type Work @default.
• W2912961005 sameAs 2912961005 @default.
• W2912961005 citedByCount "0" @default.
• W2912961005 crossrefType "journal-article" @default.
• W2912961005 hasAuthorship W2912961005A5037547064 @default.
• W2912961005 hasAuthorship W2912961005A5037599773 @default.
• W2912961005 hasAuthorship W2912961005A5069691488 @default.
• W2912961005 hasAuthorship W2912961005A5087752080 @default.
• W2912961005 hasConcept C121608353 @default.
• W2912961005 hasConcept C126322002 @default.
• W2912961005 hasConcept C142724271 @default.
• W2912961005 hasConcept C2777819096 @default.
• W2912961005 hasConcept C2778451229 @default.
• W2912961005 hasConcept C2778589982 @default.
• W2912961005 hasConcept C2779958274 @default.
• W2912961005 hasConcept C2781182431 @default.
• W2912961005 hasConcept C71924100 @default.
• W2912961005 hasConcept C90924648 @default.
• W2912961005 hasConceptScore W2912961005C121608353 @default.
• W2912961005 hasConceptScore W2912961005C126322002 @default.
• W2912961005 hasConceptScore W2912961005C142724271 @default.
• W2912961005 hasConceptScore W2912961005C2777819096 @default.
• W2912961005 hasConceptScore W2912961005C2778451229 @default.
• W2912961005 hasConceptScore W2912961005C2778589982 @default.
• W2912961005 hasConceptScore W2912961005C2779958274 @default.
• W2912961005 hasConceptScore W2912961005C2781182431 @default.
• W2912961005 hasConceptScore W2912961005C71924100 @default.
• W2912961005 hasConceptScore W2912961005C90924648 @default.
• W2912961005 hasLocation W29129610051 @default.
• W2912961005 hasOpenAccess W2912961005 @default.
• W2912961005 hasPrimaryLocation W29129610051 @default.
• W2912961005 hasRelatedWork W2010806341 @default.
• W2912961005 hasRelatedWork W2014135440 @default.
• W2912961005 hasRelatedWork W2020394999 @default.
• W2912961005 hasRelatedWork W2021004426 @default.
• W2912961005 hasRelatedWork W2265437640 @default.
• W2912961005 hasRelatedWork W2288221505 @default.
• W2912961005 hasRelatedWork W2411319260 @default.
• W2912961005 hasRelatedWork W3117977236 @default.
• W2912961005 hasRelatedWork W3141578884 @default.
• W2912961005 hasRelatedWork W2911269753 @default.
• W2912961005 hasVolume "112" @default.
• W2912961005 isParatext "false" @default.
• W2912961005 isRetracted "false" @default.
• W2912961005 magId "2912961005" @default.
• W2912961005 workType "article" @default.