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• W2912961659 abstract "Polybrominated diphenyl ethers (PBDEs) are major brominated flame retardant (BFR) chemicals with endocrine-disrupting properties. One small-scale study on humans has suggested that prenatal exposure to PBDEs is adversely related to anogenital distance (AGD) a sensitive marker for prenatal androgen exposure. The aim of the present study was to examine the associations between prenatal exposure to PBDEs and AGD among boys 0–4 years of age in a cohort study. In the Shanghai-Minhang Birth Cohort Study (S-MBCS), nine PBDE congeners were measured in cord plasma of 192 male infants. We measured anopenile distance (AGDAP) and anoscrotal distance (AGDAS) at birth, 6 months, 12 months, and 48 months of age. A total of 190 boys with neonatal concentrations of PBDEs (ng/g lipid) who had at-least one AGD measurement were included in our study. Information on potential confounding variables were collected through in-person interviews. Multiple linear regression models and generalized estimating equation (GEE) models were used to evaluate the associations between prenatal PBDEs concentrations and AGD. Among the nine congeners, BDE-47 had the highest detection rate (83.68%) and the highest median concentration (0.18 ng/g lipid). Boys who had neonatal concentration of BDE-47 or Σ4PBDEs (sum of BDE-47, BDE-99, BDE-100, and BDE-153) in the higher quartile generally had shorter AGDAP and AGDAS than those in the first quartile. Significant inverse associations were found between AGDAS and fourth quartile BDE-47 levels among boys 12 months and 48 months of age (β = −5.57, 95% confidence interval (CI): −9.89, −1.25 for 12 month of age; β = −4.32, 95% CI: −8.18, −0.46 for 48 month of age). Inverse associations were also observed between AGDAS and fourth quartile Σ4PBDEs levels among boys 12 months of age (β = −5.13, 95% CI: −9.89, −1.25). In GEE models, similar patterns of association were also observed between BDE-47 and AGDAS. Our findings provide preliminary evidence that prenatal exposure to BDE-47 and Σ4PBDEs, even at low environmental levels, may be associated with shorter AGD in boys. This data suggest that prenatal exposure to PBDEs may have adverse effects on male reproductive development. Further studies should be conducted to validate these results." @default.
• W2912961659 created "2019-02-21" @default.
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• W2912961659 date "2019-04-01" @default.
• W2912961659 modified "2023-09-26" @default.
• W2912961659 title "Prenatal polybrominated diphenyl ethers exposure and anogenital distance in boys from a Shanghai birth cohort" @default.
• W2912961659 cites W115538672 @default.
• W2912961659 cites W1546605929 @default.
• W2912961659 cites W1964334073 @default.
• W2912961659 cites W1974967017 @default.
• W2912961659 cites W1975828516 @default.
• W2912961659 cites W1979221121 @default.
• W2912961659 cites W1982429317 @default.
• W2912961659 cites W1989517537 @default.
• W2912961659 cites W1990105149 @default.
• W2912961659 cites W1990474566 @default.
• W2912961659 cites W1995028694 @default.
• W2912961659 cites W1996359328 @default.
• W2912961659 cites W2008235055 @default.
• W2912961659 cites W2010493096 @default.
• W2912961659 cites W2021405896 @default.
• W2912961659 cites W2022325590 @default.
• W2912961659 cites W2022667194 @default.
• W2912961659 cites W2027127325 @default.
• W2912961659 cites W2033772149 @default.
• W2912961659 cites W2035548948 @default.
• W2912961659 cites W2035761206 @default.
• W2912961659 cites W2040469062 @default.
• W2912961659 cites W2042938906 @default.
• W2912961659 cites W2043482823 @default.
• W2912961659 cites W2053710732 @default.
• W2912961659 cites W2056659371 @default.
• W2912961659 cites W2058759573 @default.
• W2912961659 cites W2064950621 @default.
• W2912961659 cites W2076268632 @default.
• W2912961659 cites W2079681825 @default.
• W2912961659 cites W2081195455 @default.
• W2912961659 cites W2087762803 @default.
• W2912961659 cites W2088363764 @default.
• W2912961659 cites W2089664201 @default.
• W2912961659 cites W2090543008 @default.
• W2912961659 cites W2093086887 @default.
• W2912961659 cites W2096248684 @default.
• W2912961659 cites W2097327668 @default.
• W2912961659 cites W2103060641 @default.
• W2912961659 cites W2108424907 @default.
• W2912961659 cites W2111359057 @default.
• W2912961659 cites W2115861310 @default.
• W2912961659 cites W2115938836 @default.
• W2912961659 cites W2123158727 @default.
• W2912961659 cites W2132024398 @default.
• W2912961659 cites W2137475501 @default.
• W2912961659 cites W2139632967 @default.
• W2912961659 cites W2153453855 @default.
• W2912961659 cites W2164394184 @default.
• W2912961659 cites W2164736685 @default.
• W2912961659 cites W2231657635 @default.
• W2912961659 cites W2254998737 @default.
• W2912961659 cites W2344335473 @default.
• W2912961659 cites W2345429343 @default.
• W2912961659 cites W2383985238 @default.
• W2912961659 cites W2415362227 @default.
• W2912961659 cites W2551323537 @default.
• W2912961659 cites W2572577715 @default.
• W2912961659 cites W2591599092 @default.
• W2912961659 cites W2594222307 @default.
• W2912961659 cites W2619215479 @default.
• W2912961659 cites W2734609529 @default.
• W2912961659 cites W2745445712 @default.
• W2912961659 cites W2769973426 @default.
• W2912961659 cites W2773437404 @default.
• W2912961659 cites W2783884366 @default.
• W2912961659 cites W2791408347 @default.
• W2912961659 cites W2793589675 @default.
• W2912961659 cites W2799325700 @default.
• W2912961659 cites W2804317571 @default.
• W2912961659 cites W2809882610 @default.
• W2912961659 cites W2890229985 @default.
• W2912961659 cites W2890397587 @default.
• W2912961659 cites W2891401930 @default.
• W2912961659 cites W2892298205 @default.
• W2912961659 cites W66845805 @default.
• W2912961659 cites W809077192 @default.
• W2912961659 doi "https://doi.org/10.1016/j.ijheh.2019.01.008" @default.
• W2912961659 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30713057" @default.
• W2912961659 hasPublicationYear "2019" @default.
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