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• W2912983623 abstract "Event Abstract Back to Event Identifying the retinal inputs to identified circuits passing through the superior colliculus Chen Li1, Katja Reinhard1, Emily Burke1, Steven Heynderickx1 and Karl Farrow1* 1 KU Leuven, NERF, Belgium Visually guided behavior is based on the extraction of relevant features from the visual scene and the routing of this information to the correct motor centers. At the first stage of visual processing, the retina splits the visual scene into over 30 distinct features. Each feature is embodied by a different ganglion cell type that sends visual information to one or several brain targets. To determine the rules of routing we have studied two disynaptic neuronal circuits that link the mouse retina via the superior colliculus to two midbrain nuclei – the lateral posterior nucleus (pulvinar) and the parabigeminal nucleus. It has been demonstrated that each of these midbrain nuclei receives input from different sets of collicular neurons, while optogenetic activation of each projections leads to similar avoidance behavior in mice. Here we have applied a transsynaptic viral tracing strategy to specifically label the retinal ganglion cells at the beginning of each of the two pathways. By analyzing morphological properties of the labelled cells, we can identify the ganglion cell types that are part of each of the circuits. Our data shows that each brain area receives information from a limited, partially overlapping set of retinal ganglion cells. These results indicate that the circuitry of the superior colliculus act to route specific sets of visual feature to different downstream targets. Keywords: retinal ganglion cells (RGCs), Superior colliculus (SC), midbrain nuclei, viral tracing, neural circuits Conference: 12th National Congress of the Belgian Society for Neuroscience, Gent, Belgium, 22 May - 22 May, 2017. Presentation Type: Poster Presentation Topic: Sensory and Motor Systems Citation: Li C, Reinhard K, Burke E, Heynderickx S and Farrow K (2019). Identifying the retinal inputs to identified circuits passing through the superior colliculus. Front. Neurosci. Conference Abstract: 12th National Congress of the Belgian Society for Neuroscience. doi: 10.3389/conf.fnins.2017.94.00088 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 21 Apr 2017; Published Online: 25 Jan 2019. * Correspondence: Dr. Karl Farrow, KU Leuven, NERF, Leuven, Flanders, 3000, Belgium, karl.farrow@nerf.be Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Chen Li Katja Reinhard Emily Burke Steven Heynderickx Karl Farrow Google Chen Li Katja Reinhard Emily Burke Steven Heynderickx Karl Farrow Google Scholar Chen Li Katja Reinhard Emily Burke Steven Heynderickx Karl Farrow PubMed Chen Li Katja Reinhard Emily Burke Steven Heynderickx Karl Farrow Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2912983623 date "2017-01-01" @default.
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• W2912983623 title "Identifying the retinal inputs to identified circuits passing through the superior colliculus" @default.
• W2912983623 doi "https://doi.org/10.3389/conf.fnins.2017.94.00088" @default.
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