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- W2912986852 abstract "Abstract Brain maturation extends throughout adolescence well into early adulthood. Knowledge on developmental changes is crucial for age‐appropriate pharmacotherapy. This article reviews data on maturational processes with a focus on the noradrenergic, dopaminergic, and serotonergic neurotransmitter systems.The literature was searched with a focus on studies in humans. However, since data in humans are limited animal studies were also included. All reviewed neurotransmitter systems show age‐related development processes that differentiate child and adolescent brain function from those of adult brains. Unfortunately, the state of knowledge surrounding development‐related changes remains sufficiently sparse, There is a high need for more studies on pediatric psychopharmacology and its biological underpinnings. Safety and efficacy of psychopharmacological medicines cannot be readily extrapolated from adults." @default.
- W2912986852 created "2019-02-21" @default.
- W2912986852 creator A5013680754 @default.
- W2912986852 date "2019-02-06" @default.
- W2912986852 modified "2023-09-26" @default.
- W2912986852 title "The development of monoaminergic neurotransmitter systems in childhood and adolescence" @default.
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- W2912986852 doi "https://doi.org/10.1016/j.ijdevneu.2019.02.002" @default.
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