Matches in SemOpenAlex for { <https://semopenalex.org/work/W2912987148> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2912987148 abstract "To date, the expression of both the “olfactory” receptors (OR) themselves and the components of the olfactory signaling system, «olfactory» adenylate cyclase (AC3) and “olfactory” G protein (Golf), has been found in various structural and functional parts of the kidney. In the human kidney, at least 13 genes of various “olfactory” receptors are expressed, excluding pseudogenes. Olfr 78, Gpr41, Gpr43, OR51E1, OR11H7 “olfactory” receptors have been found to play a role in the regulation of blood pressure in response to changes in the blood concentration of short-chain fatty acids, mostly produced by intestinal microbiota. The role of AC3 and G olf in renin secretion, control of SCF and obesity predisposition is shown. Olfr1393 “olfactory” receptor is supposed to be involved in glucose reabsorption in the proximal tubule of the kidney due to functional modulation of sodium glucose cotransporter Sglt1 responsible to 3–10 % glucose reabsorption in proximal tubule. Hypotheses on the relationship of “olfactory” signaling component defects with the development of pathological syndromes, such as kidney diseases, different types of ciliopathy (Bardet–Biedl, Joubert, Meckel syndromes) and valproate administration associated Fanconi syndrome, are given. The study of “olfactory” signaling components in the structure of the kidney, as well as their role, both in physiological functions and in the development of renal pathology, creates a scientific basis that will be useful not only for nephrologists and pharmacologists, but also for clinicians of other specialties from the point of view of developing new pharmacological approaches in order to target the detected defects." @default.
- W2912987148 created "2019-02-21" @default.
- W2912987148 creator A5031207299 @default.
- W2912987148 creator A5040226192 @default.
- W2912987148 date "2019-02-06" @default.
- W2912987148 modified "2023-10-18" @default.
- W2912987148 title "ECTOPIC RENAL “OLFACTORY” RECEPTORS" @default.
- W2912987148 cites W1161630335 @default.
- W2912987148 cites W1974038243 @default.
- W2912987148 cites W1990456192 @default.
- W2912987148 cites W1994863439 @default.
- W2912987148 cites W2026412750 @default.
- W2912987148 cites W2047458612 @default.
- W2912987148 cites W2056072809 @default.
- W2912987148 cites W2074904796 @default.
- W2912987148 cites W2088668994 @default.
- W2912987148 cites W2091512742 @default.
- W2912987148 cites W2097186487 @default.
- W2912987148 cites W2097404580 @default.
- W2912987148 cites W2116438701 @default.
- W2912987148 cites W2127679612 @default.
- W2912987148 cites W2144862658 @default.
- W2912987148 cites W2164368208 @default.
- W2912987148 cites W2303071827 @default.
- W2912987148 cites W2333393438 @default.
- W2912987148 cites W2526370216 @default.
- W2912987148 cites W2531830654 @default.
- W2912987148 cites W2727647516 @default.
- W2912987148 cites W2743098933 @default.
- W2912987148 cites W2891709409 @default.
- W2912987148 cites W3105188565 @default.
- W2912987148 doi "https://doi.org/10.24884/1561-6274-2019-23-1-32-36" @default.
- W2912987148 hasPublicationYear "2019" @default.
- W2912987148 type Work @default.
- W2912987148 sameAs 2912987148 @default.
- W2912987148 citedByCount "1" @default.
- W2912987148 countsByYear W29129871482019 @default.
- W2912987148 crossrefType "journal-article" @default.
- W2912987148 hasAuthorship W2912987148A5031207299 @default.
- W2912987148 hasAuthorship W2912987148A5040226192 @default.
- W2912987148 hasConcept C126322002 @default.
- W2912987148 hasConcept C134018914 @default.
- W2912987148 hasConcept C169760540 @default.
- W2912987148 hasConcept C170493617 @default.
- W2912987148 hasConcept C201792869 @default.
- W2912987148 hasConcept C2779980732 @default.
- W2912987148 hasConcept C2780091579 @default.
- W2912987148 hasConcept C2780187430 @default.
- W2912987148 hasConcept C2781231759 @default.
- W2912987148 hasConcept C56906281 @default.
- W2912987148 hasConcept C71924100 @default.
- W2912987148 hasConcept C86803240 @default.
- W2912987148 hasConcept C95444343 @default.
- W2912987148 hasConceptScore W2912987148C126322002 @default.
- W2912987148 hasConceptScore W2912987148C134018914 @default.
- W2912987148 hasConceptScore W2912987148C169760540 @default.
- W2912987148 hasConceptScore W2912987148C170493617 @default.
- W2912987148 hasConceptScore W2912987148C201792869 @default.
- W2912987148 hasConceptScore W2912987148C2779980732 @default.
- W2912987148 hasConceptScore W2912987148C2780091579 @default.
- W2912987148 hasConceptScore W2912987148C2780187430 @default.
- W2912987148 hasConceptScore W2912987148C2781231759 @default.
- W2912987148 hasConceptScore W2912987148C56906281 @default.
- W2912987148 hasConceptScore W2912987148C71924100 @default.
- W2912987148 hasConceptScore W2912987148C86803240 @default.
- W2912987148 hasConceptScore W2912987148C95444343 @default.
- W2912987148 hasLocation W29129871481 @default.
- W2912987148 hasOpenAccess W2912987148 @default.
- W2912987148 hasPrimaryLocation W29129871481 @default.
- W2912987148 hasRelatedWork W11883326 @default.
- W2912987148 hasRelatedWork W14029757 @default.
- W2912987148 hasRelatedWork W16624450 @default.
- W2912987148 hasRelatedWork W24384892 @default.
- W2912987148 hasRelatedWork W2516207 @default.
- W2912987148 hasRelatedWork W3466374 @default.
- W2912987148 hasRelatedWork W4697450 @default.
- W2912987148 hasRelatedWork W4979446 @default.
- W2912987148 hasRelatedWork W5407907 @default.
- W2912987148 hasRelatedWork W6478985 @default.
- W2912987148 isParatext "false" @default.
- W2912987148 isRetracted "false" @default.
- W2912987148 magId "2912987148" @default.
- W2912987148 workType "article" @default.