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- W2912990028 abstract "Microcystins (MCs) are produced by cyanobacterial blooms and known for their hepatotoxicity. They could cause serious damage to the reproduction of higher vertebrate mice and fish. However, few studies have focused on the reproductive toxicity of MCs to invertebrates. Giant freshwater prawn Macrobrachium rosenbergii are highly cultivated in China. During their breeding process, M. rosenbergii are often infested by cyanobacteria blooms. In the present study, to investigate the toxic effect of MCs on the testicular development of M. rosenbergii. Male M. rosenbergii were exposed to environmental relevant concentration of MC-LR for 1, 2 and 3 weeks. Results showed that MC-LR entered M. rosenbergii testis, down-regulated hemolymph testosterone (T) levels, and damaged testicular germ cells, mitochondria and cell junctions, and inhibited testicular development. Moreover, MC-LR could significantly induce the expression of gonadal development related genes in testis and eyestalk). The present results indicate that MC-LR can disrupt the testicular development of M. rosenbergii by affecting T levels and gonadal development related genes in the testis and eyestalk." @default.
- W2912990028 created "2019-02-21" @default.
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- W2912990028 date "2019-05-01" @default.
- W2912990028 modified "2023-10-10" @default.
- W2912990028 title "Microcystin-LR disturbs testicular development of giant freshwater prawn Macrobrachium rosenbergii" @default.
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- W2912990028 doi "https://doi.org/10.1016/j.chemosphere.2019.01.146" @default.
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