FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913003816> ?p ?o ?g. }

• W2913003816 endingPage "213" @default.
• W2913003816 startingPage "202" @default.
• W2913003816 abstract "Fascin, an actin-bundling protein, is present in the filopodia and lamellipodia of growth cones. However, few studies have examined lamellipodial fascin because it is difficult to observe. In this study, we evaluated lamellipodial fascin. We visualized the actin meshwork of lamellipodia in live growth cones by super-resolution microscopy. Fascin was colocalized with the actin meshwork in lamellipodia. Ser39 of fascin is a well-known phosphorylation site that controls the binding of fascin to actin filaments. Fluorescence recovery after photobleaching experiments with confocal microscopy showed that binding of fascin was controlled by phosphorylation of Ser39 in lamellipodia. Moreover, TPA, an agonist of protein kinase C, induced phosphorylation of fascin and dissociation from actin filaments in lamellipodia. Time series images showed that dissociation of fascin from the actin meshwork was induced by TPA. As fascin dissociated from actin filaments, the orientation of the actin filaments became parallel to the leading edge. The angle of actin filaments against the leading edge was changed from 73° to 15°. This decreased the elasticity of the lamellipodia by 40%, as measured by atomic force microscopy. These data suggest that actin bundles made by fascin contribute to elasticity of the growth cone." @default.
• W2913003816 created "2019-02-21" @default.
• W2913003816 creator A5024621622 @default.
• W2913003816 creator A5024916236 @default.
• W2913003816 creator A5027709863 @default.
• W2913003816 creator A5035566366 @default.
• W2913003816 creator A5056353295 @default.
• W2913003816 creator A5064449087 @default.
• W2913003816 creator A5070655967 @default.
• W2913003816 creator A5085696882 @default.
• W2913003816 date "2019-03-01" @default.
• W2913003816 modified "2023-09-30" @default.
• W2913003816 title "Fascin in lamellipodia contributes to cell elasticity by controlling the orientation of filamentous actin" @default.
• W2913003816 cites W1816409303 @default.
• W2913003816 cites W1963969404 @default.
• W2913003816 cites W1966073555 @default.
• W2913003816 cites W1967203969 @default.
• W2913003816 cites W1967972793 @default.
• W2913003816 cites W1973383826 @default.
• W2913003816 cites W1980824787 @default.
• W2913003816 cites W1981107697 @default.
• W2913003816 cites W1989902698 @default.
• W2913003816 cites W1994109845 @default.
• W2913003816 cites W1997030377 @default.
• W2913003816 cites W1999833864 @default.
• W2913003816 cites W2002612012 @default.
• W2913003816 cites W2015510735 @default.
• W2913003816 cites W2018752391 @default.
• W2913003816 cites W2023922465 @default.
• W2913003816 cites W2035918801 @default.
• W2913003816 cites W2038007769 @default.
• W2913003816 cites W2038634187 @default.
• W2913003816 cites W2055106914 @default.
• W2913003816 cites W2067440113 @default.
• W2913003816 cites W2075127308 @default.
• W2913003816 cites W2077335347 @default.
• W2913003816 cites W2086097918 @default.
• W2913003816 cites W2090676441 @default.
• W2913003816 cites W2096791952 @default.
• W2913003816 cites W2115737236 @default.
• W2913003816 cites W2121343057 @default.
• W2913003816 cites W2121588102 @default.
• W2913003816 cites W2123271440 @default.
• W2913003816 cites W2124248841 @default.
• W2913003816 cites W2124436876 @default.
• W2913003816 cites W2136841975 @default.
• W2913003816 cites W2137240530 @default.
• W2913003816 cites W2143561574 @default.
• W2913003816 cites W2146894615 @default.
• W2913003816 cites W2149241780 @default.
• W2913003816 cites W2149246707 @default.
• W2913003816 cites W2151751487 @default.
• W2913003816 cites W2152393981 @default.
• W2913003816 cites W2163523268 @default.
• W2913003816 cites W2409891140 @default.
• W2913003816 cites W2591660462 @default.
• W2913003816 cites W2591853524 @default.
• W2913003816 cites W2753761002 @default.
• W2913003816 cites W2770659015 @default.
• W2913003816 cites W2796385757 @default.
• W2913003816 cites W2899299365 @default.
• W2913003816 cites W894880941 @default.
• W2913003816 doi "https://doi.org/10.1111/gtc.12671" @default.
• W2913003816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30664308" @default.
• W2913003816 hasPublicationYear "2019" @default.
• W2913003816 type Work @default.
• W2913003816 sameAs 2913003816 @default.
• W2913003816 citedByCount "14" @default.
• W2913003816 countsByYear W29130038162020 @default.
• W2913003816 countsByYear W29130038162021 @default.
• W2913003816 countsByYear W29130038162022 @default.
• W2913003816 countsByYear W29130038162023 @default.
• W2913003816 crossrefType "journal-article" @default.
• W2913003816 hasAuthorship W2913003816A5024621622 @default.
• W2913003816 hasAuthorship W2913003816A5024916236 @default.
• W2913003816 hasAuthorship W2913003816A5027709863 @default.
• W2913003816 hasAuthorship W2913003816A5035566366 @default.
• W2913003816 hasAuthorship W2913003816A5056353295 @default.
• W2913003816 hasAuthorship W2913003816A5064449087 @default.
• W2913003816 hasAuthorship W2913003816A5070655967 @default.
• W2913003816 hasAuthorship W2913003816A5085696882 @default.
• W2913003816 hasBestOaLocation W29130038161 @default.
• W2913003816 hasConcept C109185818 @default.
• W2913003816 hasConcept C12554922 @default.
• W2913003816 hasConcept C125705527 @default.
• W2913003816 hasConcept C142669718 @default.
• W2913003816 hasConcept C1491633281 @default.
• W2913003816 hasConcept C199528912 @default.
• W2913003816 hasConcept C2778934503 @default.
• W2913003816 hasConcept C2993400109 @default.
• W2913003816 hasConcept C3620293 @default.
• W2913003816 hasConcept C55493867 @default.
• W2913003816 hasConcept C59999672 @default.
• W2913003816 hasConcept C86803240 @default.
• W2913003816 hasConcept C90301020 @default.
• W2913003816 hasConcept C95444343 @default.
• W2913003816 hasConceptScore W2913003816C109185818 @default.
• W2913003816 hasConceptScore W2913003816C12554922 @default.

• next