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- W2913006906 abstract "Study Design: This is a prospective non-randomized study of the one-year follow-up results of injecting bone marrow concentrate (BMC) into the knee joint and medial tibial metaphysis of patients with a diagnosis of knee osteoarthritis (OA). This is a Class-2 consecutive cohort study. Methods: There were 23 patients in the BMC study. The 30-minute procedure involved aspirating 55ml of bone marrow from the iliac wing, concentrating this via centrifugation to a volume of 12ml and then injecting 6ml into the medial tibial metaphysis and 6ml into the medial knee joint compartment. All the patients had a pre-treatment standing radiograph and MRI. Clinical outcome was measured with a VAS and lower extremity functional scale (LEFS) at 6 weeks, 3, 6, and 12 months. Results: The average VAS improved 59% (p<0.001) and LEFS 47% (p<0.001). There were no injection complications and no patients were made worse. No patient had knee surgery during the study. Radiographs did not improve in any patient. MRI scans showed resolution of the medial tibial metaphyseal bone inflammation in 10/12 patients. Conclusions: These results indicate a BMC knee injection has safety and efficacy and may be a reasonable non-surgical option for patients with moderate to severe knee OA." @default.
- W2913006906 created "2019-02-21" @default.
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- W2913006906 date "2018-01-01" @default.
- W2913006906 modified "2023-09-26" @default.
- W2913006906 title "Tibial Metaphysical Injection with Bone Marrow Concentrate to Treat Knee Arthritis" @default.
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