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- W2913008885 abstract "Summary The degree of transmission of hepatitis A virus ( HAV ) is inversely proportional to the socioeconomic status of a community. Serosurveys conducted at Pune, India during 1982‐98 documented significant reduction in HAV exposure of paediatric, higher socioeconomic status ( HSS ) population. Anti‐ HAV positivity ( ELISA ) in age‐stratified Pune population representing HSS and lower middle socioeconomic status ( LMSS ) (n = 1065) and infants till the age of 15 months (n = 690) was determined in 2017. Anti‐ HAV positivity in the LMSS population decreased significantly in 2017 while an increase was seen in the HSS category. The surprising rise in anti‐ HAV positivity in the HSS population reflected vaccine‐ and infection‐induced antibodies while only infection‐induced antibodies were present in the LMSS category. Lowest antibody prevalence in infants was at 12 months, the recommended age for hepatitis A vaccination. Improved hygiene and selective immunization practices impacted HAV exposure of the LMSS population. The data emphasize the need for hepatitis A vaccination irrespective of socioeconomic status." @default.
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- W2913008885 date "2019-03-05" @default.
- W2913008885 modified "2023-10-06" @default.
- W2913008885 title "Age‐stratified anti‐ <scp>HAV</scp> positivity in Pune, India after two decades: Has voluntary vaccination impacted overall exposure to <scp>HAV</scp> ?" @default.
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- W2913008885 doi "https://doi.org/10.1111/jvh.13074" @default.
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