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- W2913011685 abstract "The synthesis of a new series of 1beta-methylcarbapenems having the substituted thiazolopyrrolidine moiety is described. Their in vitro antibacterial activities against both Gram-positive including MRSA and Gram-negative bacteria were tested and the effect of substituent on the thiazole ring was investigated. A particular compound (28c) having 4'-amide substituted thiazole moiety showed the most potent antibacterial activity." @default.
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- W2913011685 date "2002-09-01" @default.
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- W2913011685 title "Synthesis and antibacterial activity of 1β-methyl-2-(5-substituted thiazolo pyrrolidin-3-ylthio)carbapenem derivatives" @default.
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- W2913011685 doi "https://doi.org/10.1016/s0223-5234(02)01397-1" @default.
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