FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913019761> ?p ?o ?g. }

• W2913019761 endingPage "99" @default.
• W2913019761 startingPage "90" @default.
• W2913019761 abstract "Abstract Aims Pharmacotherapy for methamphetamine dependence has not yet been developed in Japan or elsewhere in the world. Ifenprodil is a blocker of G protein‐activated inwardly rectifying potassium channels that play a key role in the mechanism of action of addictive substances. Our aim is to examine the safety, efficacy, and outcomes of ifenprodil for the treatment of methamphetamine dependence in a randomized, double‐blind, placebo‐controlled trial. Methods The recruitment of outpatients with methamphetamine dependence began in January 2018. The patients will be randomized into three arms: placebo, 60 mg/d ifenprodil, or 120 mg/d ifenprodil. Placebo or ifenprodil will be taken for 84 days. We will use Cerocral fine granule 4% ® (ifenprodil tartrate). Follow‐up assessments will be conducted for 84 d after the drug administration period. All of the patients will be assessed by self‐administered questionnaires and urine tests. The primary outcome will be the presence or absence of methamphetamine use during the 84‐day administration period in the 120 mg/d ifenprodil and placebo groups. Secondary outcomes will include the number of days and percentage of days of abstinence from methamphetamine use, positive urine for methamphetamine, relapse risk, and drug craving. Discussion This study is the first clinical trial of ifenprodil treatment for methamphetamine dependence and is designed as an intervention test with off‐label drug use. The present study is expected to provide evidence of the effects of ifenprodil treatment on methamphetamine dependence. Trial registry This trial was registered in the UMIN clinical trial registry ( UMIN 000030849; date of registration: January 17, 2018)." @default.
• W2913019761 created "2019-02-21" @default.
• W2913019761 creator A5002129976 @default.
• W2913019761 creator A5009334985 @default.
• W2913019761 creator A5025255521 @default.
• W2913019761 creator A5025375976 @default.
• W2913019761 creator A5027478412 @default.
• W2913019761 creator A5028679361 @default.
• W2913019761 creator A5034703679 @default.
• W2913019761 creator A5054554074 @default.
• W2913019761 creator A5061947606 @default.
• W2913019761 creator A5085486382 @default.
• W2913019761 creator A5018898191 @default.
• W2913019761 creator A5032059351 @default.
• W2913019761 date "2019-02-12" @default.
• W2913019761 modified "2023-10-09" @default.
• W2913019761 title "Study of effects of ifenprodil in patients with methamphetamine dependence: Protocol for an exploratory, randomized, double‐blind, placebo‐controlled trial" @default.
• W2913019761 cites W1501723147 @default.
• W2913019761 cites W1533708729 @default.
• W2913019761 cites W1569263281 @default.
• W2913019761 cites W1871254996 @default.
• W2913019761 cites W1962253127 @default.
• W2913019761 cites W1970756106 @default.
• W2913019761 cites W1983675510 @default.
• W2913019761 cites W1995664935 @default.
• W2913019761 cites W2007027293 @default.
• W2913019761 cites W2024215379 @default.
• W2913019761 cites W2026210109 @default.
• W2913019761 cites W2028560842 @default.
• W2913019761 cites W2029662381 @default.
• W2913019761 cites W2035887394 @default.
• W2913019761 cites W2043327777 @default.
• W2913019761 cites W2052252459 @default.
• W2913019761 cites W2058318943 @default.
• W2913019761 cites W2058606373 @default.
• W2913019761 cites W2067341862 @default.
• W2913019761 cites W2075829496 @default.
• W2913019761 cites W2078357006 @default.
• W2913019761 cites W2080980389 @default.
• W2913019761 cites W2087139802 @default.
• W2913019761 cites W2094594303 @default.
• W2913019761 cites W2095858175 @default.
• W2913019761 cites W2102306723 @default.
• W2913019761 cites W2114469645 @default.
• W2913019761 cites W2125356699 @default.
• W2913019761 cites W2145470773 @default.
• W2913019761 cites W2148499477 @default.
• W2913019761 cites W2150549953 @default.
• W2913019761 cites W2151234631 @default.
• W2913019761 cites W2151934072 @default.
• W2913019761 cites W2194134614 @default.
• W2913019761 cites W2228727390 @default.
• W2913019761 cites W2293096627 @default.
• W2913019761 cites W2327282490 @default.
• W2913019761 cites W2397930477 @default.
• W2913019761 cites W2438287464 @default.
• W2913019761 cites W247246278 @default.
• W2913019761 cites W2550602473 @default.
• W2913019761 cites W2782108388 @default.
• W2913019761 cites W2913019761 @default.
• W2913019761 cites W3194956376 @default.
• W2913019761 cites W4245119861 @default.
• W2913019761 cites W4247665917 @default.
• W2913019761 doi "https://doi.org/10.1002/npr2.12050" @default.
• W2913019761 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7292268" @default.
• W2913019761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30756527" @default.
• W2913019761 hasPublicationYear "2019" @default.
• W2913019761 type Work @default.
• W2913019761 sameAs 2913019761 @default.
• W2913019761 citedByCount "12" @default.
• W2913019761 countsByYear W29130197612019 @default.
• W2913019761 countsByYear W29130197612020 @default.
• W2913019761 countsByYear W29130197612021 @default.
• W2913019761 countsByYear W29130197612022 @default.
• W2913019761 crossrefType "journal-article" @default.
• W2913019761 hasAuthorship W2913019761A5002129976 @default.
• W2913019761 hasAuthorship W2913019761A5009334985 @default.
• W2913019761 hasAuthorship W2913019761A5018898191 @default.
• W2913019761 hasAuthorship W2913019761A5025255521 @default.
• W2913019761 hasAuthorship W2913019761A5025375976 @default.
• W2913019761 hasAuthorship W2913019761A5027478412 @default.
• W2913019761 hasAuthorship W2913019761A5028679361 @default.
• W2913019761 hasAuthorship W2913019761A5032059351 @default.
• W2913019761 hasAuthorship W2913019761A5034703679 @default.
• W2913019761 hasAuthorship W2913019761A5054554074 @default.
• W2913019761 hasAuthorship W2913019761A5061947606 @default.
• W2913019761 hasAuthorship W2913019761A5085486382 @default.
• W2913019761 hasBestOaLocation W29130197611 @default.
• W2913019761 hasConcept C126322002 @default.
• W2913019761 hasConcept C142724271 @default.
• W2913019761 hasConcept C15744967 @default.
• W2913019761 hasConcept C168563851 @default.
• W2913019761 hasConcept C170493617 @default.
• W2913019761 hasConcept C204787440 @default.
• W2913019761 hasConcept C27081682 @default.
• W2913019761 hasConcept C2776885963 @default.
• W2913019761 hasConcept C2780376393 @default.
• W2913019761 hasConcept C2780376555 @default.

• next