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- W2913157484 abstract "In December 2015, the Food and Drug Administration approved the first targeted therapy (TT) for the treatment of progressive metastatic renal cell carcinoma (mRCC). Since then, 6 small molecules and 1 monoclonal antibody have been approved in different treatment lines and indications. This article 1 Psutka S.P. Kim S.P. Gross C. et al. The impact of targeted therapy on management of metastatic renal cell carcinoma: trends in systemic therapy and cytoreductive nephrectomy utilization. Urology. 2015; 85: 442-451 Abstract Full Text Full Text PDF PubMed Scopus (30) Google Scholar describes the dissemination of TT and its impact on rates of cytoreductive nephrectomy (CN) among privately insured patients aged <65 years between 2004 and 2010 in the United States. During this period, the rate of CN in a cohort of 610 patients with mRCC considerably declined from a peak in 2005 (31.3%) to 14.8% in 2010. Regarding the study population, approximately 90% of patients had a single metastatic site. This article 1 Psutka S.P. Kim S.P. Gross C. et al. The impact of targeted therapy on management of metastatic renal cell carcinoma: trends in systemic therapy and cytoreductive nephrectomy utilization. Urology. 2015; 85: 442-451 Abstract Full Text Full Text PDF PubMed Scopus (30) Google Scholar delivers important insight in the daily practice of treating patients with mRCC showing an underestimation of CN and metastasectomy. The Impact of Targeted Therapy on Management of Metastatic Renal Cell Carcinoma: Trends in Systemic Therapy and Cytoreductive Nephrectomy UtilizationUrologyVol. 85Issue 2PreviewTo describe the dissemination of targeted therapy and its impact on rates of cytoreductive nephrectomy (CNx) and among privately insured patients with metastatic renal cell carcinoma (mRCC). Full-Text PDF" @default.
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- W2913157484 date "2015-02-01" @default.
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- W2913157484 title "Editorial Comment" @default.
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- W2913157484 doi "https://doi.org/10.1016/j.urology.2014.10.042" @default.
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