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• W2913170938 endingPage "186" @default.
• W2913170938 startingPage "174" @default.
• W2913170938 abstract "Obesity represents the second preventable mortality cause worldwide, and is very often associated with type 2 Diabetes Mellitus (T2DM). The first line treatment is lifestyle modification to weight-loss, but for those who fail to achieve the goal or have difficulty in maintaining achieved results, pharmacological treatment is needed. Few drugs are available today, because of their side effects.We aim to review actual pharmacological management of obese patients, highlighting differences between Food and Drug Administration - and European Medicine Agency-approved molecules, and pointing out self-medications readily obtainable and widely distributed.Papers on obesity, weight loss, pharmacotherapy, self- medication and diet-aid products were selected using Medline. Research articles, systematic reviews, clinical trials and meta-analyses were screened.Anti-obesity drugs with central mechanisms, such as phentermine and lorcaserin, are available in USA, but not in Europe. Phentermine/topiramate and naltrexone/bupropion combinations are now available, even though the former is still under investigation from EMA. Orlistat, with peripheral mechanisms, represents the only drug approved for weight reduction in adolescents. Liraglutide has been approved at higher dose for obesity. Anti-obesity drugs, readily obtainable from the internet, include crude-drug products and supplements for which there is often a lack of compliance to national regulatory standards.Mechanisms of weight loss drugs include the reduction of energy intake or the increase in energy expenditure and sense of satiety as well as the decrease of hunger or the reduction in calories absorption. Few drugs are approved, and differences exist between USA and Europe. Moreover, herbal medicines and supplements often sold on the internet and widely used by obese patients, present a risk of adverse effects." @default.
• W2913170938 created "2019-02-21" @default.
• W2913170938 creator A5005042369 @default.
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• W2913170938 creator A5068223964 @default.
• W2913170938 creator A5075940000 @default.
• W2913170938 creator A5080271286 @default.
• W2913170938 date "2020-02-18" @default.
• W2913170938 modified "2023-10-13" @default.
• W2913170938 title "Obesity Therapy: How and Why?" @default.
• W2913170938 cites W1492152449 @default.
• W2913170938 cites W1537391465 @default.
• W2913170938 cites W1548410362 @default.
• W2913170938 cites W1794692055 @default.
• W2913170938 cites W1963594465 @default.
• W2913170938 cites W1965273084 @default.
• W2913170938 cites W1971328164 @default.
• W2913170938 cites W1973077654 @default.
• W2913170938 cites W1978357726 @default.
• W2913170938 cites W1983547248 @default.
• W2913170938 cites W1986331352 @default.
• W2913170938 cites W1986363458 @default.
• W2913170938 cites W1988187729 @default.
• W2913170938 cites W1989576972 @default.
• W2913170938 cites W1991138114 @default.
• W2913170938 cites W1995241918 @default.
• W2913170938 cites W1997115741 @default.
• W2913170938 cites W1997598284 @default.
• W2913170938 cites W1997947019 @default.
• W2913170938 cites W2010733826 @default.
• W2913170938 cites W2017332329 @default.
• W2913170938 cites W2020982355 @default.
• W2913170938 cites W2023795430 @default.
• W2913170938 cites W2041165407 @default.
• W2913170938 cites W2042098050 @default.
• W2913170938 cites W2062262203 @default.
• W2913170938 cites W2074356217 @default.
• W2913170938 cites W2075048575 @default.
• W2913170938 cites W2076295821 @default.
• W2913170938 cites W2077494707 @default.
• W2913170938 cites W2079785535 @default.
• W2913170938 cites W2082072583 @default.
• W2913170938 cites W2084948079 @default.
• W2913170938 cites W2088690013 @default.
• W2913170938 cites W2102609831 @default.
• W2913170938 cites W2107832644 @default.
• W2913170938 cites W2107940713 @default.
• W2913170938 cites W2108150818 @default.
• W2913170938 cites W2108303166 @default.
• W2913170938 cites W2110438413 @default.
• W2913170938 cites W2110893190 @default.
• W2913170938 cites W2113503108 @default.
• W2913170938 cites W2113572448 @default.
• W2913170938 cites W2114695967 @default.
• W2913170938 cites W2115357902 @default.
• W2913170938 cites W2122772067 @default.
• W2913170938 cites W2126334399 @default.
• W2913170938 cites W2127923763 @default.
• W2913170938 cites W2132162317 @default.
• W2913170938 cites W2134860420 @default.
• W2913170938 cites W2135749311 @default.
• W2913170938 cites W2136520528 @default.
• W2913170938 cites W2137232100 @default.
• W2913170938 cites W2142938005 @default.
• W2913170938 cites W2148828094 @default.
• W2913170938 cites W2152835319 @default.
• W2913170938 cites W2153395253 @default.
• W2913170938 cites W2157849519 @default.
• W2913170938 cites W2162233634 @default.
• W2913170938 cites W2187312750 @default.
• W2913170938 cites W2318664961 @default.
• W2913170938 cites W2323053513 @default.
• W2913170938 cites W2473382031 @default.
• W2913170938 cites W2499108142 @default.
• W2913170938 cites W2510236000 @default.
• W2913170938 cites W2535659745 @default.
• W2913170938 cites W2565880689 @default.
• W2913170938 cites W2588795288 @default.
• W2913170938 cites W2604396914 @default.
• W2913170938 cites W2604582625 @default.
• W2913170938 cites W2612364086 @default.
• W2913170938 cites W2616921353 @default.
• W2913170938 cites W2742795184 @default.
• W2913170938 cites W2765153816 @default.
• W2913170938 cites W2767443138 @default.
• W2913170938 cites W2768927785 @default.
• W2913170938 cites W2770397886 @default.
• W2913170938 cites W2782270662 @default.
• W2913170938 cites W4234703934 @default.
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• W2913170938 doi "https://doi.org/10.2174/0929867326666190124121725" @default.
• W2913170938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30678612" @default.
• W2913170938 hasPublicationYear "2020" @default.
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