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• W2913202311 startingPage "2175" @default.
• W2913202311 abstract "Nine new azaphilone alkaloids, penazaphilones A–I (1–9), were isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. The structures of compounds 1–9 were elucidated based on HRESIMS, NMR, and CD spectroscopic data. The structures of 5 and 8 were confirmed by X-ray crystallographic analyses. Biological evaluation showed that compounds 1, 5, 6, and 8 inhibited the production of nitric oxide (NO) on RAW 264.7 cells stimulated by lipopolysaccharide with IC50 values of 15.29, 9.34, 9.50, and 7.05 μM, respectively. Meanwhile, they did not exhibit obvious cytotoxicity at a concentration of 50.0 μM." @default.
• W2913202311 created "2019-02-21" @default.
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• W2913202311 date "2019-01-31" @default.
• W2913202311 modified "2023-10-17" @default.
• W2913202311 title "Azaphilone Alkaloids with Anti-inflammatory Activity from Fungus <i>Penicillium sclerotiorum</i> cib-411" @default.
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• W2913202311 doi "https://doi.org/10.1021/acs.jafc.8b05628" @default.
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